Pixley F J, Wakefield A E, Banerji S, Hopkin J M
Department of Paediatrics, John Radcliffe Hospital, Oxford, UK.
Mol Microbiol. 1991 Jun;5(6):1347-51. doi: 10.1111/j.1365-2958.1991.tb00781.x.
A 6.8 kilobase fragment of mitochondrial DNA from Pneumocystis carinii encodes for apocytochrome b, NADH dehydrogenase subunits 1, 2, 3, and 6, cytochrome oxidase subunit II, and the small subunit of ribosomal RNA. Comparative sequence analysis with a series of organisms representative of the fungal and protozoan groups shows that P. carinii has, consistently, an average similarity of 60% with the fungi but only 20% with the protozoa. The data indicate homology with the fungi for this opportunistic pathogen.
来自卡氏肺孢子虫的一段6.8千碱基的线粒体DNA片段编码脱辅基细胞色素b、NADH脱氢酶亚基1、2、3和6、细胞色素氧化酶亚基II以及核糖体RNA的小亚基。与一系列代表真菌和原生动物类群的生物体进行的比较序列分析表明,卡氏肺孢子虫与真菌的平均相似度始终为60%,但与原生动物的相似度仅为20%。数据表明这种机会性病原体与真菌具有同源性。