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使用栓子保护装置进行颈动脉狭窄血管成形术和支架置入术的经验。

An experience with angioplasty and stenting of carotid artery stenosis with embolic protection devices.

作者信息

Haji-Zeinali Ali-Mohammad, Kazemi-Saleh Davood

机构信息

Department of Interventional Cardiology, Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran.

出版信息

Arch Iran Med. 2006 Apr;9(2):138-43.

Abstract

BACKGROUND

Carotid artery stenting has recently been recommended as an alternative to carotid endarterectomy by some clinicians.

OBJECTIVE

To evaluate success rate, as well as in-hospital and 30-day adverse events in our first experience in Iran for carotid artery stenting with protection devices.

METHODS

From December 2003 through July 2004, we performed 12 consecutive (9 males and 3 females) carotid artery stenting procedures. The patients had a mean age of 62 (range: 46 - 78) years. Indications for carotid artery stenting included primary lesions in all patients, stenosis > or =50% in symptomatic, and stenosis > or =80% in asymptomatic patients.

RESULTS

Carotid artery stenting was technically successful in all 12 patients. The mean +/- SD severity of stenosis before carotid artery stenting was 85 +/- 14% as compared with 15 +/- 10% after the procedure. No periprocedural death occurred. No in-hospital or 30-day minor or major stroke/death was observed.

CONCLUSION

Percutaneous stenting of the carotid artery stenosis, when a cerebral protection device is used, is feasible and effective but not without technical difficulties and potential complications. We, therefore, recommend carotid artery stenting for patients who are at high risk for undergoing carotid endarterectomy. Nevertheless, a long-learning curve may be needed for anyone who wishes to start this technique.

摘要

背景

最近一些临床医生推荐颈动脉支架置入术作为颈动脉内膜切除术的替代方法。

目的

评估在伊朗我们首次使用保护装置进行颈动脉支架置入术的成功率以及住院期间和30天内的不良事件。

方法

从2003年12月至2004年7月,我们连续进行了12例(9例男性和3例女性)颈动脉支架置入手术。患者的平均年龄为62岁(范围:46 - 78岁)。颈动脉支架置入术的适应证包括所有患者的原发性病变,有症状患者狭窄≥50%,无症状患者狭窄≥80%。

结果

12例患者的颈动脉支架置入术在技术上均获成功。颈动脉支架置入术前狭窄的平均±标准差严重程度为85±14%,术后为15±10%。围手术期无死亡发生。未观察到住院期间或30天内的轻微或严重中风/死亡。

结论

使用脑保护装置时,经皮颈动脉狭窄支架置入术是可行且有效的,但并非没有技术困难和潜在并发症。因此,我们推荐对有颈动脉内膜切除术高风险的患者进行颈动脉支架置入术。然而,任何希望开展这项技术的人可能都需要较长的学习曲线。

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