Parada David, Peña Karla, Moreira Otto
Service of Pathology, Vargas Hospital, José María Vargas School of Medicine, Central University of Venezuela, Caracas.
Arch Esp Urol. 2006 Mar;59(2):209-14. doi: 10.4321/s0004-06142006000200018.
We report herein the clinical, histological, and immunohistochemical features of a case of sarcomatoid chromophobe renal cell carcinoma.
METHODS/RESULTS: A 59-year-old woman referred a two-month history of constant right flank pain, and hematuria. A right radical nephrectomy was performed. Gross pathologic examination showed a tumor located in the lower part of the kidney with two different aspects. Histologically, the tumor was composed of two intermixed distinct morphologic components: a chromophobe renal cell carcinoma and a high-grade spindle cell sarcoma.
Our case represent a typical sarcomatoid chromophobe cell carcinoma. This unusual renal cancer has the potential to behave aggressively and to metastasize.
我们在此报告1例肉瘤样嫌色肾细胞癌的临床、组织学及免疫组化特征。
方法/结果：一名59岁女性，有持续两个月的右侧胁腹疼痛和血尿病史。行右侧根治性肾切除术。大体病理检查显示肿瘤位于肾脏下部，有两种不同表现。组织学上，肿瘤由两种不同形态成分混合组成：嫌色肾细胞癌和高级别梭形细胞肉瘤。
我们的病例代表典型的肉瘤样嫌色细胞癌。这种罕见的肾癌有侵袭性生长及转移的可能。
