Everett Allen D, Ringel Richard, Rhodes John F, Doyle Thomas P, Owada Carl Y, Holzer Ralf J, Cheatham John P, Ringewald Jeremy, Bandisode Varsha, Chen Yu-Li, Lim D Scott
Johns Hopkins University, Baltimore, Maryland 21287, and Children's Hospital of Central California, Madera, USA.
J Interv Cardiol. 2006 Apr;19(2):173-7. doi: 10.1111/j.1540-8183.2006.00128.x.
As the field of catheter-based therapies for congenital heart disease continues to expand, we lack the evidence-based data to make appropriate therapeutic decisions in the catheterization laboratory. A stumbling block to the determination of evidence-based therapies is our inability to simply and reliably share outcome data across multiple centers. We investigated whether a commonly used congenital heart disease catheterization database program (PedCath) could be used as an automatic catheterization data submission tool to a central database for outcome analysis. To test the feasibility of such a tool for collaborative outcomes research we formed a national group of seven congenital heart disease centers, the Mid-Atlantic Group of Interventional Cardiology, to warehouse and analyze catheterization data. We successfully modified PedCath to transfer the results of catheter-based therapies on 256 therapeutic procedures for atrial septal defect (ASD) closure, coarctation of the aorta angioplasty and stenting, and pulmonary and aortic balloon valvuloplasties over a 13-month pilot period. Short-term follow-up within the 13-month period was received on 31 patients. This study demonstrated the successful development of a simple process, requiring minimal data entry for investigators from around the world to share cardiac catheterization data for long-term outcome determination of catheter-based therapies for congenital heart disease.
随着先天性心脏病导管介入治疗领域的不断拓展，我们在导管室进行合理治疗决策时缺乏循证数据。确定循证治疗方法的一个绊脚石是我们无法在多个中心简单可靠地共享结果数据。我们研究了一种常用的先天性心脏病导管介入数据库程序（PedCath）是否可用作向中央数据库自动提交导管介入数据以进行结果分析的工具。为了测试这种工具用于协作性结果研究的可行性，我们组建了一个由七个先天性心脏病中心组成的全国性团体——大西洋中部介入心脏病学小组，来存储和分析导管介入数据。在为期13个月的试点期间，我们成功修改了PedCath，以传输基于导管治疗的256例治疗程序的结果，这些治疗程序包括房间隔缺损（ASD）封堵术、主动脉缩窄血管成形术和支架置入术以及肺动脉和主动脉球囊瓣膜成形术。在这13个月期间，对31例患者进行了短期随访。这项研究表明，成功开发了一个简单的流程，世界各地的研究人员只需进行最少的数据录入，就能共享心脏导管介入数据，以确定先天性心脏病基于导管治疗的长期结果。
