Bujía J, Riederer A, Zietz C, Wilmes E, Kastenbauer E
Cátedra de Otorrinolaringología, Ludwig-Masimilians-Universität München.
Acta Otorrinolaringol Esp. 1991 Nov-Dec;42(6):473-6.
Six instances of lymphoma occurring in homosexual male patients among 140 HIV-positive subjects attended at our Department of Otolaryngology were evaluated for clinical features, histopathologic features and Epstein-Barr virus (EBV) DNA. The histology of the patients was consistent with a Hodgkin's lymphoma, centroblastic lymphoma and four lymphoblastic lymphoma. High malignancy and nodal localization were characteristic of four non-Hodgkin's lymphoma, which carries a poor prognosis. The DNA in situ hybridization studies demonstrated the presence of EBV DNA sequences in the four lymphoblastic lymphoma.
在我们耳鼻喉科就诊的140例HIV阳性患者中，有6例同性恋男性患者发生淋巴瘤，对其临床特征、组织病理学特征和EB病毒（EBV）DNA进行了评估。患者的组织学类型符合霍奇金淋巴瘤、中心母细胞性淋巴瘤和4例淋巴母细胞性淋巴瘤。4例非霍奇金淋巴瘤具有高恶性和淋巴结定位的特点，预后较差。DNA原位杂交研究表明，4例淋巴母细胞性淋巴瘤中存在EBV DNA序列。
