Wattrisse G, Lecoutre D, Groux-Pante C
Service d'Anesthésie-Réanimation, C.H. Victor Provo, Roubaix.
J Mal Vasc. 1991;16(4):367-71.
A prospective trial has been carried out on 50 patients to test the efficacy and tolerance of low molecular weight heparin in surgery involving a high risk of thromboembolic complications. Tedelparin shows a tendency to reduce the frequency of post-operative thromboembolic disease in post-traumatic hip surgery. The effectiveness of the different low molecular weight heparins still remains to be quantified by comparative pharmacological studies. The alternative use of these treatments, whose high tolerance level make suitable for geriatric surgery do not exempt them from the biological monitoring of platelet count as they do not exclude the risk of heparin induced thrombocytopenia syndrome.
已对50例患者进行了一项前瞻性试验，以测试低分子量肝素在具有高血栓栓塞并发症风险的手术中的疗效和耐受性。速避凝在创伤后髋关节手术中显示出降低术后血栓栓塞性疾病发生率的趋势。不同低分子量肝素的有效性仍有待通过比较药理学研究来量化。这些治疗方法具有高耐受性，适用于老年手术，但替代使用这些方法时，由于它们不能排除肝素诱导的血小板减少综合征的风险，因此仍需对血小板计数进行生物学监测。
