Moulignier Antoine, Lascoux Caroline, Bourgarit Anne
Fondation Adolphe de Rothschild, Service de Neurologie, Paris, France.
Clin Infect Dis. 2006 Jun 1;42(11):e89-91. doi: 10.1086/503909. Epub 2006 Apr 26.
A human immunodeficiency virus (HIV) type 2 (HIV-2)-infected African patient developed inflammatory demyelinating lesions of the optic nerves, spinal cord, and brain, which coincided with a decreasing CD4 cell count and with active HIV-2 replication. This case provides evidence that HIV-2 is neurotropic, extends the range of known HIV-2-associated neurological complications, and confirms the overlap between the neurological complications of HIV type 1 and HIV-2 infection.
一名感染了2型人类免疫缺陷病毒（HIV-2）的非洲患者出现了视神经、脊髓和脑部的炎性脱髓鞘病变，这与CD4细胞计数下降以及HIV-2的活跃复制同时发生。该病例证明HIV-2具有嗜神经性，扩展了已知的与HIV-2相关的神经并发症范围，并证实了1型HIV和HIV-2感染的神经并发症之间存在重叠。
