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早期识别出现严重症状的1型人类免疫缺陷病毒血清阴性感染。

Early identification of seronegative human immunodeficiency virus type 1 infection with severe presentation.

作者信息

Chin Bum Sik, Lee Sun Hee, Kim Gab Jung, Kee Mee Kyung, Suh Soon Deok, Kim Sung Soon

机构信息

Division of AIDS, Center for Immunology and Pathology, Korea National Institute of Health, Seoul, Republic of Korea.

出版信息

J Clin Microbiol. 2007 May;45(5):1659-62. doi: 10.1128/JCM.00166-07. Epub 2007 Mar 7.

DOI:10.1128/JCM.00166-07
PMID:17344360
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1865892/
Abstract

Specific antibodies against human immunodeficiency virus (HIV), usually used for diagnosis, almost invariably become detectable within 3 months of exposure. We report on a patient whose HIV infection was identified early by a combined antigen/antibody test, but seroconversion did not occur for 7 months, until the implementation of antiretroviral therapy.

摘要

通常用于诊断的针对人类免疫缺陷病毒（HIV）的特异性抗体，几乎总是在接触后3个月内可检测到。我们报告了一名患者，其HIV感染通过联合抗原/抗体检测早期得以确诊，但直到开始抗逆转录病毒治疗，血清转化在7个月后才发生。

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本文引用的文献

1
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J Clin Microbiol. 2005 Oct;43(10):5397-9. doi: 10.1128/JCM.43.10.5397-5399.2005.
2
Incomplete HIV type 1 antibody evolution and seroreversion in acutely infected individuals treated with early antiretroviral therapy.接受早期抗逆转录病毒治疗的急性感染个体中1型人类免疫缺陷病毒抗体的不完全演变及血清学逆转
Clin Infect Dis. 2005 Mar 15;40(6):868-73. doi: 10.1086/428127. Epub 2005 Feb 18.
3
Changes over time in post-seroconversion CD4 cell counts in the Italian HIV-Seroconversion Study: 1985-2002.意大利HIV血清转化研究中血清转化后CD4细胞计数随时间的变化：1985 - 2002年
AIDS. 2005 Feb 18;19(3):331-5.
4
Tracking global patterns of N-linked glycosylation site variation in highly variable viral glycoproteins: HIV, SIV, and HCV envelopes and influenza hemagglutinin.追踪高变异性病毒糖蛋白中N-糖基化位点变异的全球模式：HIV、SIV和HCV包膜蛋白以及流感血凝素
Glycobiology. 2004 Dec;14(12):1229-46. doi: 10.1093/glycob/cwh106. Epub 2004 Jun 2.
5
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7
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