早期识别出现严重症状的1型人类免疫缺陷病毒血清阴性感染。
Early identification of seronegative human immunodeficiency virus type 1 infection with severe presentation.
作者信息
Chin Bum Sik, Lee Sun Hee, Kim Gab Jung, Kee Mee Kyung, Suh Soon Deok, Kim Sung Soon
机构信息
Division of AIDS, Center for Immunology and Pathology, Korea National Institute of Health, Seoul, Republic of Korea.
出版信息
J Clin Microbiol. 2007 May;45(5):1659-62. doi: 10.1128/JCM.00166-07. Epub 2007 Mar 7.
Abstract
Specific antibodies against human immunodeficiency virus (HIV), usually used for diagnosis, almost invariably become detectable within 3 months of exposure. We report on a patient whose HIV infection was identified early by a combined antigen/antibody test, but seroconversion did not occur for 7 months, until the implementation of antiretroviral therapy.
摘要
通常用于诊断的针对人类免疫缺陷病毒（HIV）的特异性抗体，几乎总是在接触后3个月内可检测到。我们报告了一名患者，其HIV感染通过联合抗原/抗体检测早期得以确诊，但直到开始抗逆转录病毒治疗，血清转化在7个月后才发生。
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5
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