Department of Chemistry, North Texas State University, Denton, Texas 76203.
Plant Physiol. 1968 Apr;43(4):641-4. doi: 10.1104/pp.43.4.641.
Six dichlorophenoxyacetones were synthesized and examined as potential metabolic antagonists utilizing Avena coleoptile sections and the straight growth assay procedure. Supplements of indoleacetic acid promoted growth of the sections which were inhibited by the analogs; the most inhibitory derivatives were 2,3-; 2,4-; 2,5-; and 3,4-dichlorophenoxyacetone which produced half-maximal growth responses (relative to the unaug-mented control growth) at concentrations of 106, 86, 80, and 62 mug/ml, respectively. A Lineweaver-Burk plot of the data for the inhibition by 2,4-dichlorophenoxyacetone and its reversal by indoleacetic acid appeared to represent an uncompetitive-like inhibition.
六种二氯苯氧乙酸被合成并作为潜在的代谢拮抗剂进行了研究,利用燕麦胚芽鞘切段和直生长测定程序。吲哚乙酸的添加促进了被类似物抑制的部分的生长;最具抑制性的衍生物是 2,3-;2,4-;2,5-和 3,4-二氯苯氧乙酸,它们在浓度为 106、86、80 和 62μg/ml 时分别产生相对于未经增强的对照生长的半最大生长反应(相对)。2,4-二氯苯氧乙酸抑制及其与吲哚乙酸的逆转的 Lineweaver-Burk 图似乎代表一种非竞争性抑制。