[离液序列高的阴离子对等渗糖介质中酸性溶血过程的影响]
[The effect of chaotropic anions on the course of acid hemolysis in an isotonic sugar medium].
作者信息
Ivanov I T, Danailova Iu D
机构信息
Department of Physics and Biophysics, Medical Institute, Stara Zagora, Bulgaria.
出版信息
Biofizika. 1991 Sep-Oct;36(5):833-8.
The influence of CNS-, ClO4-, NO3-, and SO4(2-) on the kinetics of acid hemolysis of erythrocytes of man, lamb, rat and rabbit was investigated. These chaotropic anions exercised strong and specific effects on the extent and time course of acid hemolysis under such conditions. In accordance with the intensity of the exercised antihemolytic effect, these anions formed a row coinciding with the Hoffmeister's row of their chaotropic action. The results demonstrate the impact of intermolecular interactions disturbance applied mainly on the cell membrane on the mechanism of acid hemolysis.
研究了中枢神经系统、高氯酸根、硝酸根和硫酸根（2-）对人、羊、大鼠和家兔红细胞酸溶血动力学的影响。在这些条件下，这些离液序列高的阴离子对酸溶血的程度和时间进程产生了强烈而特殊的影响。根据所发挥的抗溶血作用的强度，这些阴离子形成了一排，与它们离液序列高的作用的霍夫迈斯特序列相吻合。结果表明，主要作用于细胞膜的分子间相互作用干扰对酸溶血机制有影响。
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