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[有机磷农药致迟发性神经系统疾病报告(143例)]

[The report of organophosphorus pesticides cause delayed nervous system diseases (143 cases)].

作者信息

Zhang C

机构信息

Jiaojang Hospital.

出版信息

Zhonghua Shen Jing Jing Shen Ke Za Zhi. 1991 Dec;24(6):336-8, 383.

PMID:1666036
Abstract

This article reports delayed dysneuria 143 cases, 54 cases in male and 89 cases in female, age 8-59 years old. They are treated by atropine. After the cholinesterase inhibited symptoms had vanished or had improved and after the other factors had been eliminated the delayed dysneurias occur after poisoning 5.42 days. They are the peripheral neuritis, the amyotrophic lateral sclerosis, the myasthenic crisis, the peptic neuritis, the encephalitis, the mixed aphasia and the symptoms like Guillain-Barre's syndrome. Their death rates are higher in two months to the types of the myasthenic crisis, the encephalitis and the amyotrophic lateral sclerosis and to the other types of disease and the cases. Poisoned two months later, their prognosis are better and the mechanism are not very clear now.

摘要

本文报道了143例迟发性神经障碍患者,其中男性54例,女性89例,年龄8至59岁。他们接受了阿托品治疗。在胆碱酯酶抑制症状消失或改善且其他因素被排除后,中毒后5.42天出现迟发性神经障碍。这些障碍包括周围神经炎、肌萎缩侧索硬化症、重症肌无力危象、消化神经炎、脑炎、混合性失语以及类似格林-巴利综合征的症状。在两个月内,重症肌无力危象、脑炎和肌萎缩侧索硬化症类型的死亡率高于其他类型的疾病和病例。中毒两个月后,他们的预后较好,目前机制尚不清楚。

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