ARCO Plant Cell Research Institute, Dublin, California 94568.
Plant Physiol. 1985 Sep;79(1):308-10. doi: 10.1104/pp.79.1.308.
[(14)C]Acetate, [(14)C]formate, and methyl[(14)C]methionine all serve as precursors of pyrenocines A, B, and C when added to cultures of Pyrenochaeta terrestris (Hansen) Gorenz, Walker, and Larson, the pathogen responsible for disease known as pink root of onion (Allium cepa L.). This information supports the hypothesis that these metabolites are methyl-substituted polyketides in origin. Pyrenocine A arises from acetate via uncharacterized intermediates and is subsequently converted to pyrenocine B. The biosynthetic role of pyrenocine C remains uncertain.
[(14)C]乙酸盐、[(14)C]甲酸盐和甲基[(14)C]蛋氨酸在添加到洋葱致病真菌（Pyrenochaeta terrestris (Hansen) Gorenz、Walker 和 Larson）的培养物中时，均能作为苍耳菌素 A、B 和 C 的前体物质。这一信息支持了这些代谢物来源于甲基取代聚酮的假说。苍耳菌素 A 由未鉴定的中间产物从乙酸盐产生，随后转化为苍耳菌素 B。苍耳菌素 C 的生物合成作用仍不确定。
