Pierrot-Deseilligny Charles
INSERM 679 et Service de Neurologie 1, Hôpital de la Pitié Salpêtrière, 47 Bd de l'Hôpital, 75651 Paris cedex 13.
Bull Acad Natl Med. 2005 Oct;189(7):1505-15; discussion 1515-7.
Eye movements are an integral part of visual function. They are particularly well developed in frontal-eyed predator species. The abducens nuclei ensure lateral ocular motor synergy, while the oculomotor nuclei control vertical eye movements and convergence. The two main types of conjugate eye movement--saccades (image switching) and slow movements (image stabilization)--are controlled by specific brainstem premotor structures (respectively reticular and vestibular). Upstream of the brainstem, the cortical and subcortical pathways involved in eye movements are gradually being elucidated. Saccades are being used as a motor model to study the different cognitive processes, such as spatial memory, prediction and decision, involved in general movement preparation. The classical approaches based on lesion analysis, combined with transcranial magnetic stimulation and functional cerebral imaging, are contributing to our understanding of how the brain functions. Eye movements can be used for bedside diagnostic purposes, but also for sophisticated laboratory studies designed to explore the universe of cognition.
眼球运动是视觉功能不可或缺的一部分。在具有前视眼的捕食者物种中,它们尤其发达。展神经核确保眼球横向运动协同,而动眼神经核控制眼球垂直运动和辐辏。两种主要的共轭眼球运动——扫视(图像切换)和慢速运动(图像稳定)——由特定的脑干运动前结构(分别是网状结构和前庭结构)控制。在脑干上游,参与眼球运动的皮质和皮质下通路正逐渐被阐明。扫视正被用作一种运动模型,以研究参与一般运动准备的不同认知过程,如空间记忆、预测和决策。基于损伤分析、结合经颅磁刺激和功能性脑成像的经典方法,有助于我们理解大脑的功能。眼球运动不仅可用于床边诊断,还可用于旨在探索认知领域的复杂实验室研究。