Charron Cyril, Caille Vincent, Jardin François, Vieillard-Baron Antoine
Medical Intensive Care Unit, University Hospital Ambroise Paré, Assistance Publique Hôpitaux de Paris, Boulogne, France.
Curr Opin Crit Care. 2006 Jun;12(3):249-54. doi: 10.1097/01.ccx.0000224870.24324.cc.
Fluid responsiveness is a relatively new concept. It enables the efficacy of volume expansion to be predicted before use, rather than assessed afterwards, thus avoiding inappropriate fluid infusion. Echocardiography is a fantastic noninvasive tool which can directly visualize the heart and assess cardiac function. Its use was long limited by the absence of accurate indices to diagnose hypovolemia and predict the effect of volume expansion. In the last few years, several French teams have used echocardiography to develop new parameters of fluid responsiveness, taking advantage of its ability to monitor cardiac function beat by beat during the respiratory cycle.
In mechanically ventilated patients perfectly adapted to the respirator, respiratory variations in superior and inferior vena cava diameters and in left ventricular stroke volume have been validated as parameters of fluid responsiveness. In our opinion, the collapsibility index of the superior vena cava is the most reliable of these parameters, but does require transesophageal echocardiography.
Echocardiography has been widely demonstrated to predict fluid responsiveness accurately. This is now a complete and noninvasive tool able to accurately determine hemodynamic status in circulatory failure.
液体反应性是一个相对较新的概念。它能够在使用扩容治疗前预测其疗效,而非在治疗后进行评估,从而避免不恰当的液体输注。超声心动图是一种出色的非侵入性工具,可直接观察心脏并评估心脏功能。长期以来,其应用因缺乏准确的指标来诊断血容量不足和预测扩容效果而受到限制。在过去几年中,几个法国团队利用超声心动图在呼吸周期中逐搏监测心脏功能的能力,开发了新的液体反应性参数。
在完全适应呼吸机的机械通气患者中,上、下腔静脉直径以及左心室每搏输出量的呼吸变化已被确认为液体反应性参数。我们认为,上腔静脉的可塌陷指数是这些参数中最可靠的,但这确实需要经食管超声心动图检查。
超声心动图已被广泛证明能够准确预测液体反应性。现在它是一种完整的非侵入性工具,能够准确确定循环衰竭时的血流动力学状态。