Backstein David, Safir Oleg, Gross Allan
Mount Sinai Hospital, Toronto, Ontario, Canada.
Clin Orthop Relat Res. 2006 May;446:104-12. doi: 10.1097/01.blo.0000214426.52206.2c.
Massive bone defects are challenging problems in revision knee surgery. When defects are large and uncontained (without a cortical rim), structural allografts may be used to provide support for femoral and tibial components. This study reviewed 68 structural allografts at a mean of 5.4 years for clinical and radiographic outcomes. Indications for grafts included periprosthetic fracture in 19 knees, aseptic loosening in 29, infection in 11 and instability in 2. Seven knees had both femoral and tibial allografts. Multiple implant designs were used including 7 hinged prostheses. Thirteen knees (13/61) failed due to graft related complications including one graft nonunion, three aseptic loosenings, three periprosthetic fractures, four infections, and two for instability. The case of graft nonunion was successfully treated with revision fixation and autologous bone graft. There were three cases of graft resorption, two graded as severe and one as moderate. These results are satisfactory given the nature and complexity of the problem, however, reconstructive procedures require careful preoperative preparation and extensive experience in complex knee arthroplasty.
Therapeutic study, level IV (case series). See Guidelines for Authors for a complete description of levels of evidence.
在膝关节翻修手术中,巨大骨缺损是具有挑战性的问题。当缺损较大且无皮质边缘(无皮质骨边缘)时,可使用结构性同种异体骨为股骨和胫骨部件提供支撑。本研究回顾了68例结构性同种异体骨,平均随访5.4年,观察其临床和影像学结果。移植的适应证包括19例膝关节假体周围骨折、29例无菌性松动、11例感染和2例不稳定。7例膝关节同时进行了股骨和胫骨同种异体骨移植。使用了多种植入物设计,包括7个铰链式假体。13例膝关节(13/61)因移植相关并发症失败,包括1例移植骨不愈合、3例无菌性松动、3例假体周围骨折、4例感染和2例不稳定。移植骨不愈合的病例通过翻修固定和自体骨移植成功治疗。有3例移植骨吸收,2例为重度,1例为中度。鉴于问题的性质和复杂性,这些结果是令人满意的,然而,重建手术需要仔细的术前准备和复杂膝关节置换术的丰富经验。
治疗性研究,IV级(病例系列)。有关证据水平的完整描述,请参阅作者指南。