Kourounakis P N, Rekka E A
Department of Pharmaceutical Chemistry, School of Pharmacy, University of Thessaloniki, Greece.
Res Commun Chem Pathol Pharmacol. 1991 Nov;74(2):249-52.
Considering that oxygen toxicity and the related free radical attack are involved in many pathophysiological conditions, and that Allium sativum (ASP) has been used therapeutically for many of them since antiquity, we examined the intervention of ASP and alliin in free radical processes. It was found that ASP presented antioxidant activity and alliin was a very good hydroxyl radical scavenger. ASP presented good reducing ability, interacting with 1,1-diphenyl-2-picrylhydrazyl stable free radical (DPPH). These results indicate an involvement of the active Alluim sativum ingredients in free radical processes.
鉴于氧中毒及相关自由基攻击涉及许多病理生理状况，且大蒜自古以来就已被用于其中多种状况的治疗，我们研究了大蒜及蒜氨酸对自由基过程的干预作用。结果发现，大蒜具有抗氧化活性，蒜氨酸是一种非常好的羟基自由基清除剂。大蒜具有良好的还原能力，能与1,1-二苯基-2-苦基肼基稳定自由基（DPPH）发生相互作用。这些结果表明大蒜的活性成分参与了自由基过程。
