de Andrés Rachel Denis, Aillon Nancy, Bardiot Marie-Claude, Bourgeois Patrick, Mertel Stefan, Nerfin Frédéric, Romailler Gladys, Gex-Fabry Marianne, Aubry Jean-Michel
Programme bipolaire, Secteur 2-Jonction, Département de Psychiatrie, HUG, Geneva, Switzerland.
J Affect Disord. 2006 Jul;93(1-3):253-7. doi: 10.1016/j.jad.2006.03.014. Epub 2006 May 3.
To evaluate the level of satisfaction of bipolar patients participating in the structured group Life Goals Program (LGP), as well as the impact of this psychoeducative program on mood stability, treatment compliance and relapse prevention.
Forty-five patients (30 females and 15 males) with bipolar disorder were included. Their level of satisfaction was evaluated at the end of the 6-week phase 1 of LGP and after one-year participation in phase 2 (median duration 366 days, range 68-483). The impact of the LGP was also evaluated with respect to mood stability, compliance with pharmacological treatment and ability to prevent and cope with relapse. Participants' mood was rated at study entry, end of phase 1 and end of phase 2 with the Montgomery and Asberg Depression Rating Scale (MADRS) and Bech-Rafaelsen Mania Scale.
Thirty-six participants (80.0%) completed phase 1 and 17 entered phase 2. A majority of participants (82.4%) were very satisfied with the information delivered during phase 1. After attending phase 2, participants reported a subjective improvement in mood stability, relapse prevention strategies as well as coping with relapse. MADRS score decreased significantly between the beginning of phase 1 and end of phase 2 (p=0.016).
This is an open study and results need to be replicated in a randomized controlled trial.
Results of this open study suggest that the life goals psychoeducative program is well perceived by bipolar patients and has a positive impact on mood stability, relapse prevention and ability to go beyond symptoms in order to reach specific goals.
评估双相情感障碍患者参与结构化团体生活目标项目(LGP)的满意度,以及该心理教育项目对情绪稳定性、治疗依从性和预防复发的影响。
纳入45例双相情感障碍患者(30例女性和15例男性)。在LGP为期6周的第1阶段结束时以及参与第2阶段一年后(中位持续时间366天,范围68 - 483天)评估他们的满意度。还从情绪稳定性、药物治疗依从性以及预防和应对复发的能力方面评估LGP的影响。在研究入组时、第1阶段结束时和第2阶段结束时,使用蒙哥马利 - 阿斯伯格抑郁评定量表(MADRS)和贝克 - 拉法尔森躁狂量表对参与者的情绪进行评分。
36名参与者(80.0%)完成了第1阶段,17名进入第2阶段。大多数参与者(82.4%)对第1阶段提供的信息非常满意。参与第2阶段后,参与者报告在情绪稳定性、预防复发策略以及应对复发方面有主观改善。MADRS评分在第1阶段开始到第2阶段结束时显著降低(p = 0.016)。
这是一项开放性研究,结果需要在随机对照试验中重复验证。
这项开放性研究的结果表明,双相情感障碍患者对生活目标心理教育项目评价良好,该项目对情绪稳定性、预防复发以及超越症状以实现特定目标的能力有积极影响。