Department of Mental Health and Psychiatry, Bipolar Program, Geneva University Hospitals, 8, rue du 31 décembre, 1207 Geneva, Switzerland.
J Affect Disord. 2012 Feb;136(3):889-94. doi: 10.1016/j.jad.2011.09.013. Epub 2011 Oct 5.
Psychoeducation added to biological treatment enhances overall effectiveness in bipolar disorders. Here, we evaluated the long-term impact of a 2-phase structured psycho-educative group program (Life Goals Program or LGP) for bipolar patients, on parameters such as number and length of hospitalizations, mood stability, relapse prevention and social relationships.
Eighty-five patients (55 females, 30 males) with bipolar disorder (48 bipolar I, 37 bipolar II) were included retrospectively. Fifty patients participated in phase 1 and 35 participated in phases 1 and 2 of the LGP. Impact on the number and cumulative length of hospitalization was evaluated by comparing the 3-year period before and after participation in phase 1 (6 weeks) or phases 1 and 2 (median duration 24 months, range 3-74).
Number of hospitalizations significantly decreased from the 3-year period before to the 3-year period after participation in phase 1 only (p=0.017), as well as participation in both phases (p=0.035). After attending phase 1 or phases 1 and 2, a majority of participants reported subjective improvement in mood stability, efficient prevention of relapse and better coping with relapse. Perceived improvement of social relationships was significantly higher for patients who attended phases 1 and 2 than for participants in phase 1 only.
Uncontrolled retrospective study design.
Results suggest that both phase 1 only and the full 2-phase LGP have long-term positive effects on the number of hospitalizations, mood stability and relapse prevention.
在双相情感障碍的生物治疗中加入心理教育可以提高整体疗效。在这里，我们评估了一个 2 阶段结构化心理教育小组项目（生活目标计划或 LGP）对双相患者的长期影响，包括住院次数和住院时间、情绪稳定性、预防复发和社会关系等参数。
回顾性纳入 85 例双相情感障碍患者（55 名女性，30 名男性），其中 48 例为双相 I 型，37 例为双相 II 型。50 例患者参加了第 1 阶段，35 例患者参加了第 1 阶段和第 2 阶段的 LGP。通过比较参与第 1 阶段（6 周）或第 1 阶段和第 2 阶段（中位数持续时间 24 个月，范围 3-74 个月）前后的 3 年期间，评估对住院次数和累计住院时间的影响。
仅在参与第 1 阶段（p=0.017）和参与第 1 阶段和第 2 阶段（p=0.035）后，住院次数从 3 年前的时期显著减少。在参加第 1 阶段或第 1 阶段和第 2 阶段后，大多数参与者报告情绪稳定性、预防复发效率和应对复发能力的主观改善。与仅参加第 1 阶段的参与者相比，参加第 1 阶段和第 2 阶段的患者报告社会关系改善的比例显著更高。
未控制的回顾性研究设计。
结果表明，仅第 1 阶段和完整的 2 阶段 LGP 对住院次数、情绪稳定性和预防复发均有长期的积极影响。
