Shao Y F
Cancer Hospital, Chinese Academy of Medical Science, Beijing.
Zhonghua Wai Ke Za Zhi. 1991 Sep;29(9):533-6, 588.
Thirty-eight patients with multiple carcinomas of large bowel were encountered during 32 years period in our hospital. The incidence of synchronous carcinomas (SC) was 1.5% (22/1430) and metachronous carcinomas (MC) 1.1% (16/1430). Thirty-one patients were found to have two primary carcinomas and seven patients have three primary malignancies. Among the 38 patients, six also had cancers in ether organs. The authors discussed the diagnosis, tumor distribution, the cancer association with familial colonic polyposis, and hereditary colon cancer. The 5 years survival rate with SC treated by surgery was 35.7% (5/14), and was 93% (15/16) with MC. It is the authors' opinion that surgical resection should always be attempted in patients with SC and MC.
在我院32年期间共遇到38例大肠多发性癌患者。同时性癌(SC)的发生率为1.5%(22/1430),异时性癌(MC)为1.1%(16/1430)。发现31例患者有两个原发性癌,7例患者有三个原发性恶性肿瘤。在这38例患者中,有6例其他器官也有癌症。作者讨论了诊断、肿瘤分布、癌症与家族性结肠息肉病的关联以及遗传性结肠癌。手术治疗的SC患者5年生存率为35.7%(5/14),MC患者为93%(15/16)。作者认为,对于SC和MC患者应始终尝试手术切除。