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癫痫与偏头痛:二者有关联吗?

Epilepsy and migraine headache: is there a connection?

作者信息

Stevenson Sharon B

机构信息

Arkansas Children's Hospital, 800 Marshall St, Slot #512-15, Little Rock, AR 72202, USA.

出版信息

J Pediatr Health Care. 2006 May-Jun;20(3):167-71. doi: 10.1016/j.pedhc.2005.10.014.

DOI:10.1016/j.pedhc.2005.10.014
PMID:16675377
Abstract

INTRODUCTION

This study investigated the prevalence of migraine headache in pediatric patients with epilepsy and the incidence of these two disorders in the family history.

METHOD

A retrospective chart review was conducted on 475 patients with a primary diagnosis of epilepsy between January 2003 and June 2004. The patients were managed in a pediatric neurology outpatient clinic at a major teaching hospital. Cases were selected using the ICD-9-CM definition for epilepsy. Data collected included age, sex, headache, migraine, and family history.

RESULTS

The study revealed a higher prevalence of migraine in epilepsy patients (14.7%) than in the general population (2.7% to 11%). Only 4.7% had a family history of migraine, but 20.6% had a positive family history of epilepsy, supporting current ideas of the genetic etiology of some epilepsies.

DISCUSSION

This study specifically addressed epilepsy and migraine in children, but whenever a primary diagnosis is made, the potential for a coexisting disorder should be investigated.

摘要

引言

本研究调查了癫痫患儿偏头痛的患病率以及家族病史中这两种疾病的发病率。

方法

对2003年1月至2004年6月期间初诊为癫痫的475例患者进行回顾性病历审查。这些患者在一家大型教学医院的儿科神经科门诊接受治疗。病例根据国际疾病分类第九版临床修正版(ICD-9-CM)对癫痫的定义进行选择。收集的数据包括年龄、性别、头痛、偏头痛和家族病史。

结果

研究显示癫痫患者中偏头痛的患病率(14.7%)高于一般人群(2.7%至11%)。只有4.7%有偏头痛家族史,但20.6%有癫痫家族史阳性,这支持了目前关于某些癫痫遗传病因的观点。

讨论

本研究专门针对儿童癫痫和偏头痛,但无论做出何种初步诊断,都应调查是否存在共存疾病的可能性。

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Epilepsy and migraine headache: is there a connection?癫痫与偏头痛:二者有关联吗?
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Neurol Sci. 2018 Mar;39(3):519-525. doi: 10.1007/s10072-017-3232-y. Epub 2018 Jan 11.
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Migraine and epilepsy in the pediatric population.
儿童偏头痛和癫痫。
Curr Pain Headache Rep. 2014 Mar;18(3):402. doi: 10.1007/s11916-013-0402-3.
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Headache in juvenile myoclonic epilepsy.青少年肌阵挛癫痫头痛。
J Headache Pain. 2011 Apr;12(2):227-33. doi: 10.1007/s10194-011-0332-6. Epub 2011 Mar 25.