Bisca N, Duţu S
Serviciul de Fiziopatologie Respiratorie, Institutul de Ftiziologie, Bucureşti.
Pediatrie (Bucur). 1991;40(1-2):137-43.
28 Children with bronchial asthma, aged 6-18 years, were followed up for varying time intervals, between 3 months and over 5 years. In the cases studied, 7-8 functional tests were used under different clinical conditions: asymptomatic, manifested clinical form of the bronchial asthma, crisis of expiratory dyspnea in various severeness degrees. For an easy use of the method in the pediatric network, the lung functional investigation consisted only of spirographic examination (CV (vital capacity), VEMS (max. expir. ventilation per second) VEMS/CV ratio). The study has to show which of the lung functional parameters, measured on the maximum and forced spirogram, are the most useful for the best evaluation of the functional state of the asthmatic child. The VEMS value proved to be the most correct one for appreciating the presence and severeness degree of the obstructive syndrome The slight variation of the VEMS/CV ratio showed that the information given by this parameter cannot reveal enough the alteration of the lung function in child. For a better evaluation of the lung functional state in the asthmatic child, the routine spirographic examination, has to be completed with more "sensible" tests, such as FEF25-755 and MEF59 and with other functional parameters measured by plethysmographic examination (VGT, Raw).
28名年龄在6至18岁之间的支气管哮喘患儿接受了3个月至5年以上不等时间间隔的随访。在所研究的病例中，在不同临床状况下进行了7至8项功能测试：无症状、支气管哮喘的明显临床形式、不同严重程度的呼气性呼吸困难发作。为便于在儿科网络中应用该方法，肺功能检查仅包括肺量计检查（肺活量（CV）、最大呼气流量（VEMS）、VEMS/CV比值）。该研究旨在表明，在最大肺活量和用力肺活量图上测量的哪些肺功能参数对哮喘儿童功能状态的最佳评估最有用。VEMS值被证明是评估阻塞性综合征的存在和严重程度最准确的指标。VEMS/CV比值的微小变化表明，该参数提供的信息不足以充分揭示儿童肺功能的改变。为了更好地评估哮喘儿童的肺功能状态，常规肺量计检查必须辅以更“敏感”的测试，如FEF25 - 755和MEF59，以及通过体积描记法检查测量的其他功能参数（VGT、气道阻力（Raw））。
