Marica C, Galbenu P
Clinica de Ftiziologie, I.M.F. Bucureşti.
Rev Ig Med Muncii Med Soc Bacteriol Virusol Parazitol Epidemiol Pneumoftiziol Pneumoftiziol. 1990 Apr-Jun;39(2):187-91.
28 children with bronchial asthma, between 6 and 18 years old, were followed by a varied period of time 3 months - 5 years. 7-8 functional tests were carried out. The cases were studied in different clinical phases: asymptomatic, manifest, crisis of bronchial asthma. The functional pulmonary investigation included: spirographic examination [vital capacity (VC), maximum expiratory volume per second (MEVS) the VC/MEVS ratio], plethysmographic examination (VGT, Raw), measurement of the maximum instantaneous expiratory flows on the flux-volume curve (MEF50). The average value, standard residual deviation and the variation coefficient were calculated for each parameter studied in different clinical moments. The results are presented on 3 groups: per total, symptomatic and asymptomatic. The analysis of the data found showed that the variation of the parameters measured during repeated functional examinations in children with bronchial asthma ranges within broad limits (2.9%-11.5%); the broadest variation was recorded for Raw followed by MEF50 and the slightest variation was that of the VC/MEVS ratio. This indicated the lower value of the information furnished by this ratio in children in appreciating the presence or severeness degree of the obstructive syndrome.
28名6至18岁的支气管哮喘患儿接受了3个月至5年不等的随访。进行了7至8项功能测试。对这些病例在不同临床阶段进行了研究：无症状期、发作期、支气管哮喘危象期。肺功能检查包括：肺量计检查[肺活量（VC）、每秒最大呼气量（MEVS）、VC/MEVS比值]、体积描记法检查（VGT、气道阻力）、流量-容积曲线上最大瞬间呼气流量（MEF50）的测量。计算了不同临床时刻所研究的每个参数的平均值、标准剩余偏差和变异系数。结果分为3组呈现：总体、有症状和无症状。对所获数据的分析表明，支气管哮喘患儿在重复功能检查期间所测参数的变化范围较广（2.9% - 11.5%）；气道阻力的变化最广，其次是MEF50，而VC/MEVS比值的变化最小。这表明该比值在评估儿童阻塞性综合征的存在或严重程度时所提供信息的价值较低。
