Gasiorowicz Mari, Hurie Marjorie, Russell Angela, Hoxie Neil, Vergeront James
Wisconsin AIDS/HIV Program, Bureau of Communicable Diseases and Preparedness, Division of Public Health, Department of Health and Family Services, USA.
WMJ. 2006 Jan;105(1):34-9.
Hepatitis C virus (HCV) infection is the most common chronic bloodborne infection in the United States. An estimated 3.9 million persons nationally and 85,000 persons in Wisconsin are currently infected. The disease is responsible for approximately 8000 to 10,000 deaths nationally each year. This article summarizes epidemiologic trends in infection, mortality and transplants related to HCV in Wisconsin. It presents surveillance data collected during 1997-2004; HCV-related deaths during 1995-2002, with HCV as an underlying or contributing cause of death; and data for liver transplants related to HCV between 1993 and 2004. During the time periods reviewed, there were 16,668 cases of HCV infection reported, 1186 HCV-related deaths, and 356 HCV-related liver transplants involving HCV in Wisconsin. Infection rates and related adverse health outcomes related to HCV are highest in males, persons ages 35-64, Milwaukee residents, and inmates in the state correctional system. African Americans have high rates of morbidity (24% of cases) and mortality (16% of decedents), but are under-represented among recipients of HCV-related transplants (6% of recipients).
丙型肝炎病毒（HCV）感染是美国最常见的慢性血源性感染。据估计，全国有390万人感染，威斯康星州有8.5万人感染。该疾病每年在全国导致约8000至10000人死亡。本文总结了威斯康星州与HCV相关的感染、死亡率和移植的流行病学趋势。它展示了1997 - 2004年期间收集的监测数据；1995 - 2002年期间以HCV作为潜在或促成死亡原因的与HCV相关的死亡数据；以及1993年至2004年期间与HCV相关的肝移植数据。在审查的时间段内，威斯康星州报告了16668例HCV感染病例、1186例与HCV相关的死亡以及356例涉及HCV的与HCV相关的肝移植。与HCV相关的感染率和不良健康结局在男性、35 - 64岁人群、密尔沃基居民以及该州惩教系统的囚犯中最高。非裔美国人的发病率（占病例的24%）和死亡率（占死者的16%）较高，但在与HCV相关的移植受者中所占比例较低（占受者的6%）。
