Altindis Mustafa, Yilmaz Sebahattin, Dikengil Tansel, Acemoglu Hamit, Hosoglu Salih
Department of Microbiology and Clinical Microbiology, Kocatepe University School of Medicine, Afyon, Turkey.
World J Gastroenterol. 2006 Nov 14;12(42):6792-6. doi: 10.3748/wjg.v12.i42.6792.
To compare the prevalence of hepatitis viral markers among soldiers from Turkey, blood donors from Northern Cyprus, and soldiers from Northern Cyprus.
Hepatitis B surface antigen (HBsAg), anti-HCV and anti-human immunodeficiency virus (HIV) seroprevalence, HBV DNA, HCV RNA and HCV genotyping among soldiers from Turkey (group I), civil blood donors from Northern Cyprus (group II), and soldier candidates from Northern Cyprus (group III) were studied and compared to one another. In total, 17545 cases (13546 males and 3999 females with a mean age of 34.5 +/- 10.3 year, group I = 11234, group II = 5057, and group III = 1254) were included into the study.
Among all cases, HBsAg positivity rates were 2.46%, anti-HCV was 0.46% and anti-HIV was 0.00%. HBV DNA was 2.25%, HCV RNA was 0.33% in all groups. HBsAg positivity rates were 2.16% in group I, 3.00% in group II and 2.71% in group III. There was a significant difference between group I and group II (c2 = 6.11, P = 0.047 < 0.05). Anti-HCV positivity rates were 0.45% in group I, 0.45% in group II, and 0.56% in group III. Genotypes of HCV were 1b and 1a in group I, 1b, 1a and 2 in group II, and 1b, 1a in group III. HBsAg carrier rates were 2.20% in females and 2.53% in males. Anti-HCV prevalence was 0.38% in females and 0.48% in males. HBsAg positivity rates were 2.53% in individuals younger than 50, and 1.47% in older than 50. There was a significant difference between the two groups (c2 = 23.48, P = 0.001).
Prevalences of HBsAg, HCV and HIV infections in Northern Cyprus population are similar to those of Turkey.
比较土耳其士兵、北塞浦路斯献血者和北塞浦路斯士兵中肝炎病毒标志物的流行情况。
对土耳其士兵（第一组）、北塞浦路斯公民献血者（第二组）和北塞浦路斯候选士兵（第三组）的乙肝表面抗原（HBsAg）、抗丙型肝炎病毒（抗-HCV）和抗人类免疫缺陷病毒（抗-HIV）血清流行率、HBV DNA、HCV RNA及HCV基因分型进行研究并相互比较。总共17545例（13546名男性和3999名女性，平均年龄34.5±10.3岁，第一组=11234例，第二组=5057例，第三组=1254例）纳入研究。
在所有病例中，HBsAg阳性率为2.46%，抗-HCV为0.46%，抗-HIV为0.00%。所有组中HBV DNA为2.25%，HCV RNA为0.33%。第一组HBsAg阳性率为2.16%，第二组为3.00%，第三组为2.71%。第一组和第二组之间存在显著差异（χ²=6.11，P=0.047<0.05）。抗-HCV阳性率第一组为0.45%，第二组为0.45%，第三组为0.56%。第一组HCV基因型为1b和1a，第二组为1b、1a和2，第三组为1b、1a。女性HBsAg携带率为2.20%，男性为2.53%。抗-HCV流行率女性为0.38%，男性为0.48%。年龄小于50岁者HBsAg阳性率为2.53%，年龄大于50岁者为1.47%。两组之间存在显著差异（χ²=23.48，P=0.001）。
北塞浦路斯人群中HBsAg、HCV和HIV感染的流行率与土耳其相似。
