Srinivasan S R, Frerichs R R, Berenson G S
Clin Chim Acta. 1975 May 1;60(3):293-302. doi: 10.1016/0009-8981(75)90070-4.
In 447 school children 5--16 years old, in one community, serum lipid and lipoprotein levels were estimated, including total cholesterol, triglycerides, beta- and pre-beta-lipoprotein cholesterol, alpha-lipoprotein cholesterol, and the serum concentrations of beta-, pre-beta-, and alpha-lipoproteins. Mean serum cholesterol of the entire group was 188 mg/100 ml, and alpha-lipoprotein cholesterol constituted 68 mg/100 ml of this total. The levels of serum triglycerides (48.9 mg/100 ml) and pre-beta-lipoprotein (39.8 mg/100 ml) are low in children in comparison to adults. Except for pre-beta-lipoprotein levels, there was very little correlation between age and all lipids and lipoproteins in this age span. Slight differences in values were noted at certain age intervals, but there were no significant differences in values between sexes. These observations emphasize the need for evaluating lipid abnormalities in individual children by quantitating specific serum lipoproteins.
在一个社区中，对447名5至16岁的学童进行了血清脂质和脂蛋白水平评估，包括总胆固醇、甘油三酯、β-和前β-脂蛋白胆固醇、α-脂蛋白胆固醇以及β-、前β-和α-脂蛋白的血清浓度。整个组的平均血清胆固醇为188毫克/100毫升，其中α-脂蛋白胆固醇占总量的68毫克/100毫升。与成年人相比，儿童的血清甘油三酯水平（48.9毫克/100毫升）和前β-脂蛋白水平（39.8毫克/100毫升）较低。在这个年龄范围内，除了前β-脂蛋白水平外，年龄与所有脂质和脂蛋白之间几乎没有相关性。在某些年龄间隔观察到数值略有差异，但男女之间的数值没有显著差异。这些观察结果强调了通过定量特定血清脂蛋白来评估个体儿童脂质异常的必要性。
