Walker A R, Walker B F
Br Med J. 1978 Nov 11;2(6148):1336-7. doi: 10.1136/bmj.2.6148.1336.
The serum concentration of high-density lipoprotein cholesterol and the proportion it constitutes of total serum cholesterol are high in children and low in sufferers from coronary heart disease (CHD). Studies in elderly black Africans in Western Transvaal showed them to be free of CHD. HDL concentrations measured at birth and in groups of 10- to 12-year-olds, 16- to 18-year olds, and 60- to 69-year-olds showed mean values of 0.96, 1.71, 1.58, and 1.94 mmol/l (36, 66, 61, and 65 mg/100 ml) respectively; these concentrations constitued about 56%, 54%, and 45%, and 47%, of total cholesterol. Values thus did not fall from youth to age as they did in whites. Rural South African blacks live on a diet high in fibre and low in animal protein and fat; children are active; and adults remain active even when old. These high values of HDL may well be representative for a population that is active, used to a frugal traditional diet, and free from CHD.
高密度脂蛋白胆固醇的血清浓度及其在总血清胆固醇中所占比例在儿童中较高，而在冠心病患者中较低。对西德兰士瓦省老年非洲黑人的研究表明他们没有冠心病。对出生时以及10至12岁、16至18岁和60至69岁人群测量的高密度脂蛋白浓度显示，平均值分别为0.96、1.71、1.58和1.94毫摩尔/升（36、66、61和65毫克/100毫升）；这些浓度分别占总胆固醇的约56%、54%、45%和47%。因此，数值并未像白人那样从年轻时到老年时下降。南非农村黑人饮食中纤维含量高，动物蛋白和脂肪含量低；儿童活跃；成年人即使年老也保持活跃。这些高密度脂蛋白的高数值很可能代表了一个活跃、习惯传统节俭饮食且没有冠心病的人群。
