Bangard Christopher, Gossmann Axel, Kasper Hans U, Hellmich Martin, Fischer Jürgen H, Hölscher Arnulf, Lackner Klaus, Stippel Dirk L
Department of Radiology, University of Cologne, Cologne, Germany.
J Surg Res. 2006 Sep;135(1):113-9. doi: 10.1016/j.jss.2006.02.026. Epub 2006 May 4.
We sought to compare the efficacy of a monopolar radiofrequency ablation system in vivo near the portal vein and the hepatic veins in porcine liver.
Radiofrequency ablation of healthy livers near the portal vein and the hepatic veins was performed in 10 pigs with a multitined expandable electrode. Volumes and diameters of zones of ablation were assessed by magnetic resonance imaging.
Volumes (16.0 +/- 5.5 mL, P = 0.001) and diameters (4.0 +/- 0.7 cm, 3.3 +/- 0.7 cm, 3.0 +/- 0.6 cm, P <or= 0.05) of the zones of ablation near the hepatic veins were larger than that near the portal vein (7.5 +/- 4.1 mL, 3.2 +/- 0.7 cm, 2.6 +/- 0.7 cm, 2.4 +/- 0.6 cm). Energy deposition needed to ablate liver tissue was higher (P = 0.003) for radiofrequency ablation near the portal vein (3.16 +/- 1.58 kJ/mL) than for radiofrequency ablation near the hepatic veins (1.65 +/- 1.14 kJ/mL).
Higher energy deposition is needed to ablate liver tissue near the portal vein than near the hepatic veins. As a result, the zone of ablation is larger near the hepatic vein than near the portal vein.
我们试图比较单极射频消融系统在猪肝脏门静脉和肝静脉附近的体内疗效。
使用多针可扩张电极对10头猪的健康肝脏门静脉和肝静脉附近进行射频消融。通过磁共振成像评估消融区域的体积和直径。
肝静脉附近消融区域的体积（16.0±5.5 mL，P = 0.001）和直径（4.0±0.7 cm、3.3±0.7 cm、3.0±0.6 cm，P≤0.05）大于门静脉附近的消融区域（7.5±4.1 mL、3.2±0.7 cm、2.6±0.7 cm、2.4±0.6 cm）。门静脉附近射频消融所需的肝组织能量沉积（3.16±1.58 kJ/mL）高于肝静脉附近射频消融所需的能量沉积（1.65±1.14 kJ/mL，P = 0.003）。
消融门静脉附近的肝组织比消融肝静脉附近的肝组织需要更高的能量沉积。因此，肝静脉附近的消融区域比门静脉附近的消融区域更大。
