Ching Wendy, Nusse Roel
Department of Developmental Biology and Howard Hughes Medical Institute, Stanford University School of Medicine, Beckman Center, B271, Stanford, CA 94305, USA.
Cell. 2006 May 5;125(3):432-3. doi: 10.1016/j.cell.2006.04.018.
The Wnt family of signaling proteins mediates cell-cell communication during development. In this issue of Cell, Bänziger et al. (2006) and Bartscherer et al. (2006) identify Wntless/Evi, a multipass transmembrane protein in the secretory pathway of Wnt-producing cells that promotes Wnt secretion.
Wnt信号蛋白家族在发育过程中介导细胞间通讯。在本期《细胞》杂志中，班齐格等人（2006年）和巴奇雷尔等人（2006年）鉴定出了无翅型MMTV整合位点家族/Evi，这是一种在产生Wnt的细胞分泌途径中的多次跨膜蛋白，可促进Wnt分泌。
