息肉样脉络膜血管病变光动力治疗后的反复出血

Recurrent bleeding after photodynamic therapy in polypoidal choroidal vasculopathy.

作者信息

Ojima Yumiko, Tsujikawa Akitaka, Otani Atsushi, Hirami Yasuhiko, Aikawa Hiroko, Yoshimura Nagahisa

机构信息

Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Sakyo-ku, Kyoto 606-8507, Japan.

出版信息

Am J Ophthalmol. 2006 May;141(5):958-60. doi: 10.1016/j.ajo.2005.12.002.

DOI:10.1016/j.ajo.2005.12.002

PMID:16678520

Abstract

PURPOSE

To report a case of recurrent bleeding after photodynamic therapy (PDT) in an eye with polypoidal choroidal vasculopathy (PCV).

DESIGN

Interventional case report.

METHODS

A 73-year-old man was treated in the left eye for PCV with PDT.

RESULTS

Two weeks after PDT, his left eye showed extensive subretinal hemorrhage, with a slight vision loss. Three months after PDT, subretinal hemorrhage was almost absorbed. He received a second session of PDT to the remaining choroidal neovascularization. Two weeks thereafter, his left eye showed massive suprachoroidal hemorrhage with further vision loss. One month after the second PDT, visual acuity was decreased to no light perception as a result of massive vitreous hemorrhage. Although the patient underwent pars plana vitrectomy, visual acuity in the left eye remained hand motion as a result of massive suprachoroidal hemorrhage.

CONCLUSIONS

Ophthalmologists and patients should be aware of the risk of massive bleeding after PDT in eyes with PCV.

摘要

目的

报告1例息肉样脉络膜血管病变（PCV）眼在光动力疗法（PDT）后复发性出血的病例。

设计

介入性病例报告。

方法

对1例73岁男性的左眼PCV行PDT治疗。

结果

PDT后2周，其左眼出现广泛的视网膜下出血，视力稍有下降。PDT后3个月，视网膜下出血几乎吸收。对残留的脉络膜新生血管进行了第二次PDT治疗。此后2周，其左眼出现大量脉络膜上腔出血，视力进一步下降。第二次PDT后1个月，由于大量玻璃体出血，视力降至无光感。尽管患者接受了玻璃体切除术，但由于大量脉络膜上腔出血，左眼视力仍仅存手动。