Department of Ophthalmology, Vardhaman Mahavir Medical College and Safdarjung Hospital, Room No. 430 of Eye OPD, 4th Floor of OPD Building, Ansari Nagar, Ring Road, New Delhi, 110 029, India.
Department of Ophthalmology, H.I.M.S.R and H.A.H. Centenary Hopsital, Nears GK.2, Alaknanda, New Delhi, India.
Int Ophthalmol. 2021 Feb;41(2):753-765. doi: 10.1007/s10792-020-01620-0. Epub 2020 Oct 20.
Polypoidal choroidal vasculopathy is a major cause of visual disability in a vast majority of Asian population due to exudative maculopathy. Although it is a distinctive disease entity with characteristic pathophysiology, genetics, immunology and clinical features, but it is still misdiagnosed as neovascular age related macular degeneration as both the diseases are a part of pachychoroid spectrum and have some similar features. Also, there are varied options for the management of this disease, but there are no clear recommendations. So, a detailed review of the literature has been done along with special attention to the recent therapeutic advances to help the readers get a better understanding of the disease and its current management practices.
Detailed review of literature regarding polypoidal choroidal vasculopathy was done. The disease pathophysiology, genetics, risk factors, diagnostic modalities along with current treatment guidelines were extensively studied and compiled.
A comprehensive clinical update on polypoidal choroidal vasculopathy was compiled with special emphasis on the recent diagnostic modalities and treatment guidelines.
Polypoidal choroidal vasculopathy is a distinct clinical entity which can be diagnosed based on indocyanine green angiography and optical coherence tomography. Treatment includes various options like photodynamic therapy, anti VEGF agents and thermal laser ablation. A review of literature has been done and recent diagnostic modalities with management practices have been compiled for the better understanding of the disease.
由于渗出性黄斑病变，息肉样脉络膜血管病变是亚洲绝大多数人群视力障碍的主要原因。虽然它是一种具有独特病理生理学、遗传学、免疫学和临床特征的疾病实体，但由于这两种疾病都属于脉络膜增厚谱的一部分，具有一些相似的特征，因此仍被误诊为新生血管性年龄相关性黄斑变性。此外，这种疾病的治疗方法多种多样，但没有明确的建议。因此，对文献进行了详细的回顾，并特别关注最近的治疗进展，以帮助读者更好地了解这种疾病及其当前的管理实践。
对息肉样脉络膜血管病变的相关文献进行了详细的回顾。广泛研究并编写了该疾病的病理生理学、遗传学、危险因素、诊断方法以及当前的治疗指南。
对息肉样脉络膜血管病变进行了全面的临床更新，特别强调了最近的诊断方法和治疗指南。
息肉样脉络膜血管病变是一种明确的临床实体，可以通过吲哚青绿血管造影和光学相干断层扫描进行诊断。治疗包括多种选择，如光动力疗法、抗血管内皮生长因子药物和热激光消融。对文献进行了综述，并对最近的诊断方法和管理实践进行了编译，以更好地了解该疾病。
