Finney Nathaniel S
Institute of Organic Chemistry, University of Zurich, Winterthurerstrasse 190, CH-8057, Switzerland.
Curr Opin Chem Biol. 2006 Jun;10(3):238-45. doi: 10.1016/j.cbpa.2006.04.025. Epub 2006 May 5.
The properties of organic fluorophores are difficult to predict, even in simple cases. Fluorescent probes--which combine fluorescent properties with the equally challenging problem of molecular recognition--are even more difficult to develop. Combinatorial approaches to the development of such molecules are a new but promising endeavor, and reviewing the state of the art delineates the near-and long-term possibilities.
即使在简单的情况下，有机荧光团的性质也很难预测。荧光探针——将荧光性质与同样具有挑战性的分子识别问题结合在一起——则更难开发。开发此类分子的组合方法是一项新的但很有前景的努力，回顾当前的技术水平可以勾勒出近期和长期的可能性。
