Erol Demet D
Department of Anesthesiology and Reanimation, School of Medicine, Kocatepe University, Afyon, Turkey.
Saudi Med J. 2006 May;27(5):714-6.
Henoch-Schonlein purpura HSP is a multisystem disease and immunoglobulin A-mediated vasculitis with a self-limited course affecting the skin, joints, gastrointestinal tract, and kidneys. It is the most common form of acute small-vessel vasculitis primarily affecting children. Severe renal and central nervous system disease may lead to life-threatening conditions, and immunosuppressive agents and plasmapheresis may be needed. The cause of HSP is unknown; immunizations, certain food allergies, insect bites, infection, and some medications may play a role in the development of the disease. Perioperative management for liver and kidney functions is very important for anesthetized patients with HSP. We report the perioperative management of a patient with HSP for appendectomy.
过敏性紫癜（HSP）是一种多系统疾病，是由免疫球蛋白A介导的血管炎，病程呈自限性，可累及皮肤、关节、胃肠道和肾脏。它是急性小血管炎最常见的形式，主要影响儿童。严重的肾脏和中枢神经系统疾病可能导致危及生命的情况，可能需要使用免疫抑制剂和血浆置换。HSP的病因尚不清楚；免疫接种、某些食物过敏、昆虫叮咬、感染和一些药物可能在该疾病的发生中起作用。对于接受麻醉的HSP患者，肝肾功能的围手术期管理非常重要。我们报告了1例因阑尾炎行阑尾切除术的HSP患者的围手术期管理情况。
