Kac Gilberto, Silveira Erika Aparecida, Oliveira Lívia Costa de, Mari Jair de Jesus
Instituto de Nutrição Josué de Castro, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.
Cad Saude Publica. 2006 May;22(5):999-1007. doi: 10.1590/s0102-311x2006000500012. Epub 2006 Apr 28.
The aim was to investigate factors potentially associated with minor psychiatric disorders, including maternal nutritional status variables. A cohort was studied with 479 women 15-45 years of age. The reduced General Health Questionnaire (GHQ-12 items) was applied at nine months post-partum with the 312 women who had completed follow-up. Minor psychiatric disorder was defined as a GHQ score of > or = 4 points and was treated as the response variable. Statistical analysis used hierarchical multivariate logistic regression models. The prevalence of minor psychiatric morbidity was 54.2% (95%CI: 48.6-59.7). According to the final model, the following variables remained statistically associated with minor psychiatric morbidity: level 1: total family income (1st quartile: OR = 2.71, 95%CI: 1.42-5.19; 2nd quartile: OR = 2.13; 95%CI: 1.13-4.04); level 3: body fat > or = 30% (OR = 1.66; 95%CI: 1.03-2.65). In conclusion, low income and obesity were the only factors potentially associated with minor psychiatric disorders, even after adjusting for confounding variables, while there are few studies relating maternal nutritional status and minor psychiatric morbidity.
目的是调查可能与轻度精神障碍相关的因素,包括母亲的营养状况变量。对479名年龄在15至45岁之间的女性组成的队列进行了研究。对完成随访的312名女性在产后九个月应用简化的一般健康问卷(GHQ-12项)。轻度精神障碍定义为GHQ评分≥4分,并作为反应变量。统计分析使用分层多变量逻辑回归模型。轻度精神疾病的患病率为54.2%(95%CI:48.6-59.7)。根据最终模型,以下变量仍与轻度精神疾病在统计学上相关:第1级:家庭总收入(第1四分位数:OR = 2.71,95%CI:1.42-5.19;第2四分位数:OR = 2.13;95%CI:1.13-4.04);第3级:体脂≥30%(OR = 1.66;95%CI:1.03-2.65)。总之,即使在调整混杂变量后,低收入和肥胖仍是可能与轻度精神障碍相关的唯一因素,而很少有研究涉及母亲营养状况与轻度精神疾病发病率之间的关系。