Niewold Timothy B, Bundrick John B
Department of Rheumatology, Hospital for Special Surgery, New York, New York 10021, USA.
Am J Hematol. 2006 Jun;81(6):454-7. doi: 10.1002/ajh.20602.
We report the case of an immunocompetent woman who developed disseminated intravascular coagulation (DIC) due to acute cytomegalovirus (CMV) infection and was successfully treated with plasma exchange. Extensive investigations revealed no other cause for her DIC, and she did not have any recurrence after more than 1 year of follow up. Clinically evident DIC due to CMV infection is most common in immunosuppressed patients. The one previously reported immunocompetent patient with DIC due to acute CMV infection died from the illness despite traditional supportive measures. Plasma exchange is a novel therapy that should be considered in this situation.
我们报告了一例免疫功能正常的女性病例，该患者因急性巨细胞病毒（CMV）感染而发生弥散性血管内凝血（DIC），并通过血浆置换成功治愈。广泛的检查未发现她发生DIC的其他原因，在随访1年多后她未出现任何复发情况。临床上，由CMV感染引起的明显DIC在免疫抑制患者中最为常见。先前报道的一例因急性CMV感染发生DIC的免疫功能正常患者，尽管采取了传统的支持措施，仍因病死亡。血浆置换是一种在这种情况下应予以考虑的新疗法。
