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2
The HELLP syndrome: clinical issues and management. A Review.HELLP综合征:临床问题与管理。综述。
BMC Pregnancy Childbirth. 2009 Feb 26;9:8. doi: 10.1186/1471-2393-9-8.
3
Intensive plasma exchange increases a disintegrin and metalloprotease with thrombospondin motifs-13 activity and reverses organ dysfunction in children with thrombocytopenia-associated multiple organ failure.强化血浆置换可增加具有血小板反应蛋白基序的解聚素和金属蛋白酶13的活性,并逆转血小板减少症相关性多器官功能衰竭患儿的器官功能障碍。
Crit Care Med. 2008 Oct;36(10):2878-87. doi: 10.1097/ccm.0b013e318186aa49.
4
Bench-to-bedside review: thrombocytopenia-associated multiple organ failure--a newly appreciated syndrome in the critically ill.从实验台到病床的综述:血小板减少相关的多器官功能衰竭——危重症中一种新认识的综合征
Crit Care. 2006;10(6):235. doi: 10.1186/cc5064.
5
Plasma exchange therapy in HELLP syndrome: a single-center experience.HELLP综合征的血浆置换治疗:单中心经验
Turk J Gastroenterol. 2006 Jun;17(2):99-102.
6
Disseminated intravascular coagulation due to cytomegalovirus infection in an immunocompetent adult treated with plasma exchange.巨细胞病毒感染导致免疫功能正常的成人发生弥散性血管内凝血,接受了血浆置换治疗。
Am J Hematol. 2006 Jun;81(6):454-7. doi: 10.1002/ajh.20602.
7
Severe secondary deficiency of von Willebrand factor-cleaving protease (ADAMTS13) in patients with sepsis-induced disseminated intravascular coagulation: its correlation with development of renal failure.脓毒症诱发的弥散性血管内凝血患者中血管性血友病因子裂解蛋白酶(ADAMTS13)的严重继发性缺乏:其与肾衰竭发生的相关性
Blood. 2006 Jan 15;107(2):528-34. doi: 10.1182/blood-2005-03-1087. Epub 2005 Sep 27.
8
Thrombotic microangiopathy: differential diagnosis, pathophysiology and therapeutic strategies.血栓性微血管病:鉴别诊断、病理生理学及治疗策略
Mt Sinai J Med. 2005 May;72(3):166-75.
9
The role of plasma exchange in HELLP syndrome.血浆置换在HELLP综合征中的作用。
Clin Appl Thromb Hemost. 2005 Apr;11(2):211-7. doi: 10.1177/107602960501100211.
10
Fatal congenital thrombotic thrombocytopenic purpura with apparent ADAMTS13 inhibitor: in vitro inhibition of ADAMTS13 activity by hemoglobin.伴有明显ADAMTS13抑制剂的致命性先天性血栓性血小板减少性紫癜:血红蛋白对ADAMTS13活性的体外抑制作用
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血小板减少相关的多器官功能衰竭或严重溶血、肝酶升高、产后病例血小板计数低。

Thrombocytopenia-associated multiple organ failure or severe haemolysis, elevated liver enzymes, low platelet count in a postpartum case.

作者信息

Jagia Manish, Taqi Salah, Hanafi Mahmoud, Aisha Fakeir

机构信息

Department of Anaesthesia and Intensive Care, Al Jahra Hospital, Kuwait.

出版信息

Indian J Anaesth. 2013 Jan;57(1):62-5. doi: 10.4103/0019-5049.108568.

DOI:10.4103/0019-5049.108568
PMID:23716769
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3658339/
Abstract

Thrombocytopenia-associated multiple organ failure (TAMOF) is a thrombotic microangiopathic syndrome that includes thrombotic thrombocytopenic purpura, secondary thrombotic microangiopathy, and disseminated intravascular coagulation. We report a case of postpartum female who presented with TAMOF or severe Haemolysis, elevated liver enzymes, low platelet count (HELLP) which was managed with plasma exchange. This case report is to make clinicians aware that TAMOF, severe HELLP, and other differential diagnosis in a postpartum case have a thin differentiating line and plasma exchange can be considered as one of the management options.

摘要

血小板减少相关的多器官功能衰竭(TAMOF)是一种血栓性微血管病综合征,包括血栓性血小板减少性紫癜、继发性血栓性微血管病和弥散性血管内凝血。我们报告一例产后女性患者,她出现了TAMOF或严重的溶血、肝酶升高、血小板计数降低(HELLP)综合征,通过血浆置换进行治疗。本病例报告旨在让临床医生意识到,产后病例中的TAMOF、严重HELLP及其他鉴别诊断之间的鉴别界限很细微,血浆置换可被视为治疗选择之一。