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非过敏性血管运动性鼻炎的问卷调查评估及危险因素识别

Questionnaire evaluation and risk factor identification for nonallergic vasomotor rhinitis.

作者信息

Brandt Dominique, Bernstein Jonathan A

机构信息

Center for Epidemiology and Biostatistics, Cincinnati Children's Hospital Medical Center, Ohio, USA.

出版信息

Ann Allergy Asthma Immunol. 2006 Apr;96(4):526-32. doi: 10.1016/S1081-1206(10)63546-6.

Abstract

BACKGROUND

Chronic rhinitis, a prevalent primary care disorder associated with significant comorbidities, is often incorrectly diagnosed. As a result, inappropriate treatment leads to higher health care costs and poor clinical outcomes.

OBJECTIVE

To verify whether responses to specific questions may help in the diagnosis of nonallergic vasomotor rhinitis (NAVMR).

METHODS

A questionnaire listing allergic and nonallergic triggers was blindly distributed to 100 random new patients with chronic rhinitis in an allergist's office. Questionnaire and physician diagnoses were compared. Allergic triggers included cat, dog, feathers, other furry animals, and symptoms during the spring, summer, and fall seasons. Nonallergic triggers included temperature changes, diesel and car exhaust, tobacco smoke, perfumes and fragrances, incense, cleaning products, newsprint, hairspray, and alcoholic beverages, spicy foods, or eating.

RESULTS

The construct validity and internal consistency indicated that the questionnaire was a good tool for diagnosing NAVMR. Multivariate analysis revealed that the absence of outdoor symptoms in the spring (odds ratio [OR], 7.76; 95% confidence interval [CI], 1.18-51.22; P = .03), no parental history of allergy (OR, 5.16; 95% CI, 1.05-25.20; P = .04), no symptoms around cats (OR, 3.82; 95% CI, 0.59-24.83; P = .16), the presence of symptoms around perfumes and fragrances (OR, 4.875; 95% CI, 1.05-22.60; P = .04), and age at symptom onset (OR, 1.08; 95% CI, 1.02-1.14; P = .008) were predictive of NAVMR.

CONCLUSIONS

Specific questionnaire responses may help primary care physicians accurately diagnose NAVMR. Questions asked of patients by physicians to diagnose allergic rhinitis do not correlate well with physician diagnosis.

摘要

背景

慢性鼻炎是一种常见的基层医疗疾病,常伴有多种合并症,且常被误诊。因此,不恰当的治疗会导致更高的医疗成本和不良的临床结局。

目的

验证对特定问题的回答是否有助于诊断非过敏性血管运动性鼻炎(NAVMR)。

方法

在过敏症专科医生办公室,将一份列出过敏性和非过敏性触发因素的问卷随机分发给100名新的慢性鼻炎患者。对问卷结果和医生的诊断进行比较。过敏性触发因素包括猫、狗、羽毛、其他毛茸茸的动物,以及春、夏、秋季节出现的症状。非过敏性触发因素包括温度变化、柴油和汽车尾气、烟草烟雾、香水和香料、香、清洁产品、新闻纸、发胶,以及酒精饮料、辛辣食物或进食。

结果

结构效度和内部一致性表明,该问卷是诊断NAVMR的良好工具。多变量分析显示,春季无户外症状(比值比[OR],7.76;95%置信区间[CI],1.18 - 51.22;P = 0.03)、无父母过敏史(OR,5.16;95% CI,1.05 - 25.20;P = 0.04)、接触猫时无症状(OR,3.82;95% CI,0.59 - 24.83;P = 0.16)、接触香水和香料时有症状(OR,4.875;95% CI,1.05 - 22.60;P = 0.04),以及症状出现时的年龄(OR,1.08;95% CI,1.02 - 1.14;P = 0.008)可预测NAVMR。

结论

特定的问卷回答可能有助于基层医疗医生准确诊断NAVMR。医生为诊断过敏性鼻炎向患者询问的问题与医生的诊断相关性不佳。

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