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[急性缺氧时不同耐缺氧能力大鼠脑的电生理学研究]

[An electrophysiological study of the brain of rats with different resistances to oxygen deficiency in acute hypoxia].

作者信息

Krapivin S V, Romanova V E, Voronina T A, Luk'ianova L D

出版信息

Fiziol Zh SSSR Im I M Sechenova. 1991 Jul;77(7):1-6.

PMID:1668148
Abstract

The Fourier spectre of power (SP) and bioelectrical activity of the cortex, hippocampus and hypothalamus were studied in unrestrained rats with high (HR) and low (LR) resistance to oxygen deficiency before and after their stay at the "altitude" of about 11,000 m. After acute hypobaric hypoxia there were the EEG changes in LR rats: displacement of the SP peak in low-frequency activity and decreasing of absolute power of all the ranges of SP. In one hour after the "altitude", these EEG parameters were restored. The EEG of the HR rats was not altered. The cortex of the brain seems to be the most susceptible to hypoxia.

摘要

对在海拔约11000米“高空”停留前后,对缺氧具有高(HR)和低(LR)耐受性的自由活动大鼠的大脑皮层、海马体和下丘脑的功率傅里叶频谱(SP)和生物电活动进行了研究。急性低压缺氧后,LR大鼠出现脑电图变化:SP峰向低频活动偏移,且SP所有频段的绝对功率降低。在“高空”停留一小时后,这些脑电图参数恢复正常。HR大鼠的脑电图未发生改变。大脑皮层似乎对缺氧最为敏感。

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