Khan J, Burnham E L, Moss M
Department of Neurology, Division of Pulmonary, Allergy and Critical Care Medicine, Emory University School of Medicine, Atlanta, GA, USA.
Minerva Anestesiol. 2006 Jun;72(6):401-6.
Illnesses commonly encountered in the ICU, such as sepsis, have frequently been associated with neuromuscular weakness and may play a role in the development of CIM and CIP, whose incidence in the critically ill is greater than initially reported. Although difficult to diagnose from history and clinical/laboratory findings alone, the use of electromyographic and nerve conduction testing is helpful in establishing these diagnoses. Information regarding prognosis of these disorders is limited, and there are no specific therapies that improve outcome. Acquired neuromuscular weakness in the ICU affects a significant number of patients and may continue to affect their quality of life long after discharge. Although diagnostic techniques are readily available, additional research is necessary to obtain adequate prognostic information and therapeutic options for these patients.
重症监护病房（ICU）中常见的疾病，如脓毒症，常常与神经肌肉无力相关，并且可能在危重病性肌病（CIM）和危重病性神经病（CIP）的发生中起作用，其在危重症患者中的发病率高于最初报道。尽管仅根据病史和临床/实验室检查结果难以诊断，但肌电图和神经传导测试有助于确立这些诊断。关于这些疾病预后的信息有限，并且没有能改善预后的特异性治疗方法。ICU中获得性神经肌肉无力影响大量患者，并且可能在出院后很长时间继续影响他们的生活质量。尽管诊断技术容易获得，但仍需要进一步研究以获取这些患者足够的预后信息和治疗选择。
