点滴状副银屑病的紫外线B光疗法——我们对29例患者的治疗经验
UVB therapy of pityriasis lichenoides--our experience with 29 patients.
作者信息
Pavlotsky F, Baum S, Barzilai A, Shpiro D, Trau H
机构信息
Phototherapy Unit, Department of Dermatology, Sheba Medical Center, Tel Hashomer and Sackler School of Medicine, Tel-Aviv University, Israel.
出版信息
J Eur Acad Dermatol Venereol. 2006 May;20(5):542-7. doi: 10.1111/j.1468-3083.2006.01531.x.
BACKGROUND
Pityriasis lichenoides comprises a clinical and pathological spectrum of disorders. So far no highly effective treatment has been reported. Previous small studies have suggested that ultraviolet B (UVB) is a good alternative.
METHODS
This is a retrospective analysis of 29 pityriasis lichenoides patients treated in our institution with broad- or narrow-band UVB during the period 1996-2002. Twenty-one of these patients had one or more previous unsuccessful treatments.
RESULTS
Complete response was achieved in 93.1% in both treatment groups, with 73% of them still relapse free after a mean follow-up of 58 and 38 months in broad- and narrow-band UVB treatment groups, respectively. Mild side-effects were observed in about one-third of the patients.
CONCLUSION
We believe both forms of UVB are a good option for pityriasis lichenoides and should be considered as the first line in generalized cases interested in treatment.
背景
苔藓样糠疹包括一系列临床和病理疾病。迄今为止，尚未报道有高效的治疗方法。先前的小型研究表明，紫外线B（UVB）是一种不错的选择。
方法
这是一项对1996年至2002年期间在我们机构接受宽谱或窄谱UVB治疗的29例苔藓样糠疹患者的回顾性分析。这些患者中有21例曾接受过一次或多次治疗但未成功。
结果
两个治疗组的完全缓解率均为93.1%，宽谱和窄谱UVB治疗组分别平均随访58个月和38个月后，其中73%的患者仍未复发。约三分之一的患者观察到轻微副作用。
结论
我们认为两种形式的UVB都是治疗苔藓样糠疹的良好选择，对于有治疗意愿的全身性病例应将其视为一线治疗方法。
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