Stresser David M
Drug Metab Rev. 2006;38(1-2):3-12. doi: 10.1080/03602530600569745.
David Kupfer's research career spanned 50 years and he authored or co-authored over 160 papers and book chapters. Although best known for his work centering on cytochrome P450 metabolism of prostaglandins, steroids, and proestrogenic compounds, David's research also contributed key advances in the areas of P450 induction and catalytic mechanism, breast cancer therapy, and analytical methodology. His research is reviewed here.
大卫·库普弗的研究生涯长达50年,他独自撰写或与人合著了160多篇论文和书籍章节。尽管他最出名的是围绕细胞色素P450对前列腺素、类固醇和雌激素前体化合物的代谢所开展的工作,但大卫的研究在P450诱导和催化机制、乳腺癌治疗以及分析方法等领域也取得了关键进展。在此对他的研究进行综述。