Kobayashi Yuka, Sugitani Soichi, Morita Shinichi, Nonaka Masaya, Saito Yuko, Fujiwara Shinichi, Hori Takashiro, Iiri Takao
Dept. of Gasteroenterology, Tachikawa General Hospital.
Gan To Kagaku Ryoho. 2006 May;33(5):655-7.
We report a case of a 67-year-old woman diagnosed with advanced esophageal cancer. She was treated with chemo-radiotherapy (5-FU/CDDP therapy and irradiation) initially, and primary lesion was well controlled. Two and a half years after first treatment, a chest CT showed multiple lung metastasis, which were confirmed by thoraco-laparoscopy. We chose docetaxel/CDDP combination chemotherapy, because of severe side effects due to the first treatment. After 3 courses, lung metastatic lesions were reduced. The following courses combining docetaxel-nedaplatin were done as ambulatory treatment. These regimens could be one choice for recurrent esophageal cancer, especially FP therapy-resistant or intolerant cases.
我们报告一例67岁女性被诊断为晚期食管癌的病例。她最初接受了化疗放疗（5-氟尿嘧啶/顺铂疗法及放疗），原发灶得到了良好控制。首次治疗两年半后，胸部CT显示多发肺转移，经胸腹腔镜检查得以证实。由于首次治疗出现严重副作用，我们选择了多西他赛/顺铂联合化疗。3个疗程后，肺转移病灶缩小。后续采用多西他赛-奈达铂联合的疗程作为门诊治疗。这些方案可能是复发性食管癌的一种选择，尤其是对氟尿嘧啶和顺铂疗法耐药或不耐受的病例。
