日本男性工人轮班工作与糖尿病发病关系的长期纵向研究。
Long-term longitudinal study on the relationship between alternating shift work and the onset of diabetes mellitus in male Japanese workers.
作者信息
Suwazono Yasushi, Sakata Kouichi, Okubo Yasushi, Harada Hideto, Oishi Mitsuhiro, Kobayashi Etsuko, Uetani Mirei, Kido Teruhiko, Nogawa Koji
机构信息
Department of Occupational and Environmental Medicine, Graduate School of Medicine, Chiba University, Chiba, Japan.
出版信息
J Occup Environ Med. 2006 May;48(5):455-61. doi: 10.1097/01.jom.0000214355.69182.fa.
OBJECTIVE
This study investigated the effect of alternating shift work (ASW) on the onset of diabetes mellitus in Japanese workers compared with onset in day-shift work (DSW).
METHODS
A longitudinal study was carried out on a DSW group (n = 3203) and ASW group (n = 2426) of a steel company who received their annual health checkups over a 10-year period between 1991 and 2001. The association between job schedule type and onset of diabetes mellitus (glycated hemoglobin A1c > or =6.0% or medication) was investigated by multivariate pooled logistic regression analyses.
RESULTS
The odds ratio (95% confidence interval) for the development of diabetes mellitus in the ASW group compared with the DSW group was 1.35 (1.05-1.75).
CONCLUSIONS
Our study revealed that the ASW is an independent risk factor for the onset of diabetes mellitus.
目的
本研究调查了与日班工作（DSW）相比，交替轮班工作（ASW）对日本工人糖尿病发病的影响。
方法
对一家钢铁公司的日班组（n = 3203）和交替轮班组（n = 2426）进行了一项纵向研究，这些工人在1991年至2001年的10年期间接受了年度健康检查。通过多变量合并逻辑回归分析研究工作时间表类型与糖尿病发病（糖化血红蛋白A1c≥6.0%或用药）之间的关联。
结果
与日班组相比，交替轮班组患糖尿病的优势比（95%置信区间）为1.35（1.05 - 1.75）。
结论
我们的研究表明，交替轮班工作是糖尿病发病的一个独立危险因素。
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