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LZ complexity distance of DNA sequences and its application in phylogenetic tree reconstruction.

作者信息

Li Bin, Li Yi Bing, He Hong Bo

机构信息

School of Information Science and Engineering, Central South University, Changsha 410083, China.

出版信息

Genomics Proteomics Bioinformatics. 2005 Nov;3(4):206-12. doi: 10.1016/s1672-0229(05)03028-7.

DOI:10.1016/s1672-0229(05)03028-7
PMID:16689687
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5172548/
Abstract

DNA sequences can be treated as finite-length symbol strings over a four-letter alphabet (A, C, T, G). As a universal and computable complexity measure, LZ complexity is valid to describe the complexity of DNA sequences. In this study, a concept of conditional LZ complexity between two sequences is proposed according to the principle of LZ complexity measure. An LZ complexity distance metric between two nonnull sequences is defined by utilizing conditional LZ complexity. Based on LZ complexity distance, a phylogenetic tree of 26 species of placental mammals (Eutheria) with three outgroup species was reconstructed from their complete mitochondrial genomes. On the debate that which two of the three main groups of placental mammals, namely Primates, Ferungulates, and Rodents, are more closely related, the phylogenetic tree reconstructed based on LZ complexity distance supports the suggestion that Primates and Ferungulates are more closely related.

摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e3a4/5172548/e8d374cbfc75/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e3a4/5172548/f4a352ea5ac8/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e3a4/5172548/e8d374cbfc75/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e3a4/5172548/f4a352ea5ac8/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e3a4/5172548/e8d374cbfc75/gr2.jpg

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本文引用的文献

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Bioinformatics. 2003 Mar 1;19(4):513-23. doi: 10.1093/bioinformatics/btg005.
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