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PTreeRec:基于基因组BLAST距离的系统发育树重建

PTreeRec: Phylogenetic Tree Reconstruction based on genome BLAST distance.

作者信息

Deng Riqiang, Huang Mingsong, Wang Jinwen, Huang Yuansen, Yang Jie, Feng Jinghua, Wang Xunzhang

机构信息

State Key Laboratory of Biocontrol, School of Life Science, Sun Yat-sen (Zhongshan) University, Guangzhou 510275, People's Republic of China.

出版信息

Comput Biol Chem. 2006 Aug;30(4):300-2. doi: 10.1016/j.compbiolchem.2006.04.003. Epub 2006 Jun 21.

Abstract

Phylogenetic Tree Reconstruction (PTreeRec) is a web-based tool for automatic phylogeny inferences from whole-genome sequences, which accepts files of DNA sequences in the FASTA format and allows users to save the output tree file, and displays the inferred tree through an applet in a web browser. PTreeRec involves three basic steps. First, regions of maximal segment pairs (MSPs) based on an all-against-all pairwise comparison of genomes are located. Second, a distance matrix is calculated from MSP scores or coverage. Finally, a phylogenetic tree is reconstructed by the neighbor-joining method.

摘要

系统发育树重建(PTreeRec)是一种基于网络的工具,用于从全基因组序列中自动推断系统发育,它接受FASTA格式的DNA序列文件,允许用户保存输出的树文件,并通过网页浏览器中的小程序显示推断出的树。PTreeRec包括三个基本步骤。首先,基于基因组的全基因组两两比较定位最大片段对(MSP)区域。其次,根据MSP得分或覆盖率计算距离矩阵。最后,通过邻接法重建系统发育树。

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