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卵黄蛋白原基因表达作为无脊椎动物紫贻贝内分泌干扰的生物标志物。

Vitellogenin gene expression as a biomarker of endocrine disruption in the invertebrate, Mytilus edulis.

作者信息

Puinean Alin-Mirel, Rotchell Jeanette M

机构信息

Department of Biology and Environmental Science, School of Life Sciences, University of Sussex, Falmer, Brighton, BN1 9QJ, UK.

出版信息

Mar Environ Res. 2006 Jul;62 Suppl:S211-4. doi: 10.1016/j.marenvres.2006.04.035. Epub 2006 Apr 18.

Abstract

Vitellogenin levels are often used as a biomarker of endocrine disruption in fish. For invertebrates, there is a general lack of knowledge regarding endocrine regulation and, consequently, there are few direct biomarkers of endocrine disruption in such species. This study focuses on the marine mussel Mytilus edulis, which is often employed in biomonitoring studies. A partial vitellogenin mRNA has been isolated and gene expression quantified using real-time PCR.

摘要

卵黄蛋白原水平常被用作鱼类内分泌干扰的生物标志物。对于无脊椎动物,人们对其内分泌调节普遍缺乏了解,因此这类物种中几乎没有内分泌干扰的直接生物标志物。本研究聚焦于常被用于生物监测研究的海洋贻贝紫贻贝。已分离出部分卵黄蛋白原mRNA,并使用实时PCR对基因表达进行了定量。

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