• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

猪链球菌感染:清迈大学医院的41例病例系列

Streptococcus suis infection: a series of 41 cases from Chiang Mai University Hospital.

作者信息

Wangkaew Suparaporn, Chaiwarith Romanee, Tharavichitkul Prasit, Supparatpinyo Khuanchai

机构信息

Department of Medicine, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand.

出版信息

J Infect. 2006 Jun;52(6):455-60. doi: 10.1016/j.jinf.2005.02.012. Epub 2006 May 11.

DOI:10.1016/j.jinf.2005.02.012
PMID:16690131
Abstract

OBJECTIVES

The objectives of this study were (1) to assess the clinical manifestations, treatment, and outcome of Streptococcus suis infection in adult patients in northern Thailand, (2) to evaluate the anti-microbial sensitivity pattern and (3) to determine the predicting factors of high mortality rate.

METHODS

A retrospective study was conducted at Chiang Mai University Hospital from May 2000 to December 2002. Anti-microbial susceptibility test was performed by agar disk diffusion and the minimal inhibitory concentration (MIC) by E-test.

RESULTS

Forty-one patients (32 men and nine women, mean age 51 years) with S. suis infection were identified. Three patients had a history of exposure to pig or pork and one patient had a history of raw beef consumption. Clinical manifestations included infective endocarditis, meningitis, sepsis, spondylodiscitis, and endophthalmitis in 16, 13, 10, 1, and 1 patients, respectively. The overall mortality rate was 19.5%. On univariate analysis, low serum albumin, high serum total bilirubin, low platelet, and rapid onset of illness were significantly correlated with high mortality rate. All isolates were sensitive to penicillin (mean MIC90=0.027 microg/ml).

CONCLUSIONS

S. suis infection is not uncommon in northern Thailand. High suspicion and early detection are important and could lead to the successful treatment.

摘要

目的

本研究的目的是(1)评估泰国北部成年患者感染猪链球菌的临床表现、治疗及预后,(2)评估抗菌药物敏感性模式,(3)确定高死亡率的预测因素。

方法

于2000年5月至2002年12月在清迈大学医院进行一项回顾性研究。采用琼脂纸片扩散法进行抗菌药物敏感性试验,并用E试验测定最低抑菌浓度(MIC)。

结果

共确定41例猪链球菌感染患者(32例男性,9例女性,平均年龄51岁)。3例患者有接触猪或猪肉史,1例患者有食用生牛肉史。临床表现包括感染性心内膜炎、脑膜炎、败血症、脊椎盘炎和眼内炎,分别有16例、13例、10例、1例和1例。总死亡率为19.5%。单因素分析显示,低血清白蛋白、高血清总胆红素、低血小板及疾病快速起病与高死亡率显著相关。所有分离株对青霉素敏感(平均MIC90 = 0.027μg/ml)。

结论

猪链球菌感染在泰国北部并不少见。高度怀疑和早期发现很重要,可带来成功的治疗。

相似文献

1
Streptococcus suis infection: a series of 41 cases from Chiang Mai University Hospital.猪链球菌感染:清迈大学医院的41例病例系列
J Infect. 2006 Jun;52(6):455-60. doi: 10.1016/j.jinf.2005.02.012. Epub 2006 May 11.
2
Streptococcus suis infection and risk factors for mortality.猪链球菌感染及死亡风险因素
J Infect. 2008 Nov;57(5):392-6. doi: 10.1016/j.jinf.2008.08.006. Epub 2008 Oct 2.
3
Streptococcus suis infection in Thailand.泰国的猪链球菌感染
J Med Assoc Thai. 2002 Jun;85 Suppl 1:S109-17.
4
Streptococcus suis infection: clinical features and diagnostic pitfalls.猪链球菌感染:临床特征与诊断陷阱
Southeast Asian J Trop Med Public Health. 2003 Mar;34(1):154-8.
5
Hearing and vestibular loss in Streptococcus suis infection from swine and traditional raw pork exposure in northern Thailand.泰国北部猪链球菌感染导致的听力和前庭功能丧失与接触猪及传统生猪肉有关。
J Laryngol Otol. 2009 Aug;123(8):857-62. doi: 10.1017/S0022215109004939. Epub 2009 Mar 11.
6
Streptococcus suis infection.猪链球菌感染
J Microbiol Immunol Infect. 2005 Oct;38(5):306-13.
7
[Clinical features and outcome of infection of type 2 Streptococcus suis in human].[人感染2型猪链球菌的临床特征及转归]
Sichuan Da Xue Xue Bao Yi Xue Ban. 2007 Sep;38(5):874-8.
8
Streptococcus suis infection in Hong Kong.香港的猪链球菌感染
QJM. 1995 Jan;88(1):39-47.
9
Streptococcus suis meningitis in adults in Vietnam.越南成人的猪链球菌脑膜炎
Clin Infect Dis. 2008 Mar 1;46(5):659-67. doi: 10.1086/527385.
10
Streptococcus suis meningitis: the newest serious infectious disease.猪链球菌脑膜炎:最新的严重传染病。
J Med Assoc Thai. 2008 May;91(5):654-8.

引用本文的文献

1
Novel zoonotic Streptococcus suis lineage causes infective endocarditis with high mortality in Thailand.新型人畜共患猪链球菌谱系在泰国引发感染性心内膜炎,死亡率很高。
Eur J Clin Microbiol Infect Dis. 2025 Aug 13. doi: 10.1007/s10096-025-05225-2.
2
Clinical characteristics and trends in the antimicrobial susceptibility profile of Streptococcus suis infections in a large tertiary hospital, Thailand, 2007-2023.2007 - 2023年泰国一家大型三级医院猪链球菌感染的临床特征及抗菌药物敏感性谱变化趋势
PLoS Negl Trop Dis. 2025 May 19;19(5):e0013110. doi: 10.1371/journal.pntd.0013110. eCollection 2025 May.
3
: A Possible Emerging Zoonotic Pathogen in Romania.
罗马尼亚一种可能新出现的人畜共患病原体。
Microorganisms. 2025 Feb 4;13(2):335. doi: 10.3390/microorganisms13020335.
4
Contamination of and Serotype 2 in Raw Pork and Edible Pig Organs: A Public Health Concern in Chiang Mai, Thailand.生猪肉和可食用猪器官中的污染及2型血清型:泰国清迈的一个公共卫生问题。
Foods. 2024 Jul 3;13(13):2119. doi: 10.3390/foods13132119.
5
Human Infections in Thailand: Epidemiology, Clinical Features, Genotypes, and Susceptibility.泰国的人类感染:流行病学、临床特征、基因型及易感性
Trop Med Infect Dis. 2022 Nov 8;7(11):359. doi: 10.3390/tropicalmed7110359.
6
From Farm to Fork: as a Model for the Development of Novel Phage-Based Biocontrol Agents.从农场到餐桌:开发新型噬菌体生物防治剂的模型。
Viruses. 2022 Sep 9;14(9):1996. doi: 10.3390/v14091996.
7
The Ability of Nuclease-Resistant RNA Aptamer against Serotype 2, Strain P1/7 to Reduce Biofilm Formation In Vitro.抗核酸酶 RNA 适体对血清型 2 株 P1/7 的体外生物膜形成减少的能力。
Molecules. 2022 Jun 17;27(12):3894. doi: 10.3390/molecules27123894.
8
Screening for Virulence-Related Genes via a Transposon Mutant Library of Serotype 2 Using a Larvae Infection Model.利用幼虫感染模型通过2型血清型转座子突变体文库筛选毒力相关基因
Microorganisms. 2022 Apr 21;10(5):868. doi: 10.3390/microorganisms10050868.
9
Clinical and Epidemiological Characteristics of Infections in Catalonia, Spain.西班牙加泰罗尼亚地区感染的临床与流行病学特征
Front Med (Lausanne). 2021 Dec 8;8:792233. doi: 10.3389/fmed.2021.792233. eCollection 2021.
10
Burden of disease and productivity impact of Streptococcus suis infection in Thailand.泰国猪链球菌感染的疾病负担和生产力影响。
PLoS Negl Trop Dis. 2021 Jan 22;15(1):e0008985. doi: 10.1371/journal.pntd.0008985. eCollection 2021 Jan.