Berz Jennifer Bender, Carter Alice S, Wagmiller Robert L, Horwitz Sarah M, Murdock Karla Klein, Briggs-Gowan Margaret
Department of Psychology, University of Massachusetts Boston, Boston, Massachusetts 02125-3393, USA.
J Pediatr Psychol. 2007 Mar;32(2):154-66. doi: 10.1093/jpepsy/jsj123. Epub 2006 May 11.
The combined contribution of neonatal, perinatal, and maternal health, demographic, environmental, and family psychosocial factors to early onset asthma and wheezing in a healthy birth cohort was examined.
Participants included 1,158 ethnically and socioeconomically diverse parents of 2- and 3-year olds who completed mailed questionnaires.
Asthma and wheezing prevalence was 8.4 and 8.1%, respectively. Asthma during pregnancy, smoking in the home, and being male increased risk for asthma diagnosis and wheezing whereas social support minimized risk for both. Shorter gestational age, exposure to violence, and maternal anxiety increased risk for wheezing. The negative impact of smoking in the home was greatest for children with shorter gestational ages and mothers with asthma during pregnancy.
Findings confirm and extend previous work documenting demographic risks and highlight smoking, violent events, and social support in early onset asthma and wheezing. Findings illustrate the need for ecologically based interventions to treat asthma and wheezing in young children.
研究新生儿、围产期和孕产妇健康、人口统计学、环境以及家庭心理社会因素对健康出生队列中早发性哮喘和喘息的综合影响。
参与者包括1158名2至3岁儿童的父母，他们来自不同种族和社会经济背景，通过邮寄问卷的方式完成调查。
哮喘和喘息的患病率分别为8.4%和8.1%。孕期哮喘、家中吸烟以及男性性别会增加哮喘诊断和喘息的风险，而社会支持则会降低两者的风险。孕周较短、遭受暴力以及孕产妇焦虑会增加喘息的风险。家中吸烟对孕周较短的儿童以及孕期患有哮喘的母亲所生儿童的负面影响最大。
研究结果证实并扩展了先前关于人口统计学风险的研究，突出了早发性哮喘和喘息中的吸烟、暴力事件以及社会支持因素。研究结果表明需要采取基于生态的干预措施来治疗幼儿的哮喘和喘息。
