Anderson Jeri L, Daniels Robert D
Division of Surveillance, Hazard Evaluations, and Field Studies, National Institute for Occupational Safety and Health, PHS/DHHS, 4676 Columbia Pkwy, Mail Stop R-44, Cincinnati, OH 45226, USA.
Health Phys. 2006 Jun;90(6):544-53. doi: 10.1097/01.HP.0000194230.29763.0c.
Inclusion of dose from work-related medical x-ray examinations with occupational external dose in an epidemiological study may reduce misclassification of exposures and provide more accurate assessment of leukemia risk from occupational exposure to ionizing radiation. In a multi-site leukemia case-control study, annual bone marrow doses due to work-related x-ray examinations given between 1943 and 1966 were estimated for cases and controls employed at five nuclear facilities. Only active bone marrow dose from photofluorographic chest and routine lumbar spine x rays were included. Bone marrow dose assigned for a single exposure ranged from 1.0 to 1.4 mGy. Mean and median cumulative bone marrow doses for each of the five sites from work-related x-ray examinations ranged from 2.0 to 14 mGy and 2.1 to 8.8 mGy, respectively. Results suggest that bone marrow dose from work-related photofluorographic and lumbar spine x-ray examinations given during the time period of this study may be significant compared to occupational bone marrow dose.
在一项流行病学研究中，将与工作相关的医学X射线检查剂量与职业外照射剂量纳入考量，可能会减少暴露的错误分类，并更准确地评估职业性接触电离辐射导致白血病的风险。在一项多地点白血病病例对照研究中，对在五个核设施工作的病例和对照，估算了1943年至1966年间因与工作相关的X射线检查所致的年度骨髓剂量。仅纳入了荧光摄影胸部X光和常规腰椎X光的活性骨髓剂量。单次照射的骨髓剂量范围为1.0至1.4毫戈瑞。五个地点各自因与工作相关的X射线检查所致的平均和累积骨髓剂量，分别为2.0至14毫戈瑞和2.1至8.8毫戈瑞。结果表明，在本研究期间进行的与工作相关的荧光摄影和腰椎X光检查的骨髓剂量，与职业骨髓剂量相比可能具有显著性。
