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[家族性无症状菌尿的试验评估]

[Trial evaluation of familial asymptomatic bacteriuria].

作者信息

Olszewska-Hebanowska E, Hebanowski M, Galiński J

机构信息

Zakładu Podstawowej Opieki Zdrowotnej AM w Gdańsku.

出版信息

Pol Tyg Lek. 1991;46(40-42):759-63.

PMID:1669153
Abstract

Between September 1, 1987 and December 1, 1988, 57 cases of asymptomatic bacteriuria were distinguished in the group of 2,898 schoolgirls, aged between 15 and 20 years (mean 16.7 years). For screening purposes Griess'test modified by Sleigh was used. Bacteriologic tests have shown, that 12 out 57 mothers (21.05%) and 5 out of 39 sisters (12.82%) suffered from asymptomatic bacteriuria, while this pathology was diagnosed in 61 (2.10%) out of all control population, i.e. 66 girls. Incidence of the asymptomatic bacteriuria was 4.55% in the 66 mothers. The differences in the incidence of the infection between the whole population and mothers of the control group, and between sisters and mothers of girls with asymptomatic bacteriuria were statistically significant (p < .001 and p < .01, respectively). History of the urinary tract infections was significantly more frequent in girls with asymptomatic bacteriuria, their mothers and sisters than in the control group. Type of bacterial strains isolated from the urine, similar sanitary conditions in these families as well as the lack of ultrasonographically and renographically diagnosed urinary pathologies in 11 out of 13 girls whose mothers and sisters suffered from asymptomatic bacteriuria suggest that familial asymptomatic bacteriuria may have a genetic background.

摘要

在1987年9月1日至1988年12月1日期间,在2898名年龄在15至20岁(平均16.7岁)的女学生群体中鉴别出57例无症状菌尿症。为进行筛查,采用了经斯利修改的格里斯试验。细菌学检测表明,57名母亲中有12名(21.05%)、39名姐妹中有5名(12.82%)患有无症状菌尿症,而在所有对照人群(即66名女孩)中有61名(2.10%)被诊断出患有这种病症。66名母亲中无症状菌尿症的发病率为4.55%。整个群体与对照组母亲之间以及无症状菌尿症女孩的姐妹与母亲之间感染发病率的差异具有统计学意义(分别为p <.001和p <.01)。无症状菌尿症女孩及其母亲和姐妹的尿路感染病史明显比对照组更为常见。从尿液中分离出的细菌菌株类型、这些家庭相似的卫生条件以及13名母亲和姐妹患有无症状菌尿症的女孩中有11名经超声和肾造影检查未诊断出尿路病变,这表明家族性无症状菌尿症可能具有遗传背景。

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