del Angel A R, Quirarte G, Feria-Velasco A
Divisione de Biología del Desarrollo, Unidad de Investigación Biomédica de Occidente, IMSS, Guadalajara, Jalisco, México.
Arch Invest Med (Mex). 1990 Oct-Dec;21(4):325-30.
It is known that malnourished rats show a reduction of body weight gain during postnatal development. However, more data are needed regarding the effects of protein restriction to rats fed a corn-bean and corn diets, on their body and cephalic growth. In the present work, 4 groups of adult female rats were fed during 5 weeks with diets with 23% protein (C); 8% protein (HP); corn (M); and corn-bean (M-F). Rats were mated with adult healthy male rats and the corresponding diets were continued during gestation and suckling periods. At 24 days of age, the pups of HP, M and M-F diet groups, only gained 48%, 30% and 18% respectively, in their body weight, whereas the body-length parameters (LNC and LNRC) showed a reduction of 20%, 35%, and 45%, respectively for the same diet groups. The cephalic measurements showed a significant reduction in the pups of the restricted diets when compared to data obtained in the group under control diet. The degree of alteration in the morphometric parameters was progressively greater with HP, M, and M-F, respectively.
已知营养不良的大鼠在出生后发育过程中体重增加会减少。然而,关于蛋白质限制对喂食玉米-大豆和玉米日粮的大鼠的身体和头部生长的影响,还需要更多数据。在本研究中,4组成年雌性大鼠在5周内分别喂食含23%蛋白质的日粮(C)、含8%蛋白质的日粮(HP)、玉米日粮(M)和玉米-大豆日粮(M-F)。大鼠与成年健康雄性大鼠交配,并在妊娠和哺乳期继续喂食相应的日粮。在24日龄时,HP、M和M-F日粮组的幼崽体重分别仅增加了48%、30%和18%,而体长参数(LNC和LNRC)在相同日粮组中分别减少了20%、35%和45%。与对照日粮组的数据相比,限制日粮组幼崽的头部测量结果显示出显著降低。形态计量学参数的改变程度分别在HP、M和M-F组中逐渐增大。